Background: Cervical cancer is one of the leading causes of death among women facing gynecological problems. It requires early detection by various screening methods. Aims and Objectives: The current research aimed to assess the diagnostic utility of pap smear cytology and visual inspection of acetic acid (VIA) as a screening test for various cervical lesions. Materials and Methods: The current prospective study was conducted on 210 non-pregnant women. Cervical pap smears were taken and reported according to the revised Bethesda system, 2014. VIA examination was also done, and any dense opaque aceto-white lesion observation near the squamo-columnar junction was reported as VIA positive. The findings of pap smear cytology and VIA were correlated with findings of histopathology. Results: Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of pap smear cytology for the diagnosis of cervical lesions were found to be 90.16%, 85.22%, 89.43%, 86.2%, and 88.09%, respectively; while sensitivity, specificity, PPV, NPV, and diagnostic accuracy of VIA for the diagnosis of cervical lesions were found to be 88.37%, 55.55%, 76%, 75%, and 75.71%, respectively. Our study showed a substantial degree of agreement between pap smear cytology and histopathology for the diagnosis of cervical lesions with Cohen’s kappa value being 0.755. Conclusion: The current study revealed that pap smear and VIA have high sensitivity with good diagnostic accuracy for the detection of neoplastic cervical lesions, which indicate that they can be used as an efficient screening tool for the detection of cervical lesions in their earlier stages.
Background: Fine-needle aspiration cytology (FNAC) is the most common, cost-effective, and time-efficient cytological diagnostic procedure and is used routinely in cases of swelling or lymph node enlargement at accessible sites. FNAC plays an important role in diagnosing benign and malignant lesions of peripheral lymphadenopathy cases and also provides a valuable screening test. Aims and Objectives: In this study, we aimed to evaluate various cytomorphological manifestations of lymphadenopathies and the suggestive cases of tuberculous lymphadenitis were divided based on their cytomorphological patterns. Materials and Methods: The current prospective study was conducted in the Department of Pathology, SSMC, Rewa, M.P. A total of 150 cases of peripheral lymphadenopathy were subjected to FNAC and were categorized based on their cytological findings. The cases which showed features suggestive of tuberculous lymphadenitis were further categorized into four distinct cytological patterns (I to IV). Results: Out of 150 cases of peripheral lymphadenopathies, the most common lesion diagnosed cytologically was reactive lymphadenitis (41.3%) followed by tuberculous lymphadenitis in 38.7% cases. The different patterns of tuberculous lymphadenitis on microscopy were divided into four categories from I to IV with pattern I being the most frequently seen (53.5%). Conclusion: Our study highlighted the various morphological patterns of lymphadenopathy and the most common lesion diagnosed was reactive lymphadenitis. The present study found that FNAC is an effective screening tool for diagnosing benign and malignant lymphadenopathies and also to study the cytomorphological patterns in cases of tuberculous lymphadenitis. It reduces the need for surgical intervention and for the early diagnosis and management of patients with peripheral lymphadenopathy.
Background: In 2016, International academy of cytology (IAC) has established a standardized approach for reporting breast fine-needle aspiration cytology (FNAC) by categorizing the lesions in five tier system from C1 to C5 to standardize reporting, which will enhance Breast fine-needle aspiration biopsy cytology performance, interpretation, and reporting. Aims and Objectives: The aim of the study was to categorize FNAC cases according to The IAC Yokohama System and evaluate the diagnostic ability of FNAC. Materials and Methods: The current prospective analytical study was carried out in the Department of Pathology, Shyam Shah Medical College, Rewa, Madhya Pradesh, for a period of 15 months from January 2021 to March 2022 (15 months). A total of 100 cases were included in the study based on inclusion criteria. The results were analyzed based on cytological reporting and P value calculated. Results: Among the 100 cases studied highest number of cases were from the age group of 21–30 years with 29% (n=29). The most common breast laterality affected was left with 69% of affected cases. The maximum number of cases, 69% (n=69) of the total, were found to be categorized under the category C2 (benign) which was followed by Category C5 (Malignant) seen in 13% (n=13). About 9% (n=9) of the total cases were categorized as suspicious of malignancy (C4). Atypical Lesion (C3) and Unsatisfactory Lesions (C1) were categorized in 5% (n=5) and 4% (n=4) of the total cases, respectively. Conclusion: FNAC is a minimally invasive, quick, and efficient pre-operative diagnostic tool that can also be used for postoperative breast lump follow-up to prevent recurrences. FNAC using IAC Yokohama system is a rapid and effective method for the primary categorization of palpable breast lumps and provides better clarity to the clinicians in the management of the patient and can reduce unnecessary surgeries.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.