O mollissima de Jatropha(Pohl) O Baill é um arbusto autóctone nativo da vegetação da Caatinga, encontrado em grande parte da região semi-árida do Nordeste brasileiro, utilizado na cultura popular para fins terapêuticos. O látex de Jatropha e seus extratos foram avaliados quanto à composição química, identificando os principais metabólitos secundários e suas atividades farmacológicas utilizando métodos qualitativos e quantitativos. Sua toxicidade foi investigada através da dose tóxica aguda em ratos Wistar, sua ação antioxidante foi investigada de acordo com o método fotocolorimétrico do radical livre DPPH, e sua ação antibacteriana foi investigada através de concentração inibitória mínima e concentração bactericida mínima. Fenóis, taninos, flavonóides e saponinas foram detectados em látex e em outros extratos, exceto o extrato aquoso.Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pyogenes, Streptococcus mutans e Enterococcus faecalis) e cepas Gram-negativas ( Shigella flexneri, Escherichia coli, Klebsiella pneumoniae, Salmonella typhimurium e Pseudomonas aeruginosa ) em várias diluições juntamente com o extrato hidroalcoólico. O látex de J. mollissima também apresentou baixa toxicidade aguda em ratos. Portanto, os resultados obtidos nesta pesquisa corroboram o uso popular de J. mollissima e seu potencial terapêutico.

This study aimed to identify the presence of Trypanosoma vivax DNA in the colostrum of infected goats and to explore the possibility of transmission for neonates fed using colostrum collected from infected goats. We used twelve goats in the final third of gestation with an age of approximately 24 months. Six goats were inoculated intravenously with 0.5mL of blood containing approximately 1.25x105 trypomastigotes of T. vivax, and six remained uninfected. The presence of T. vivax in colostrum was evaluated by Polymerase Chain Reaction (PCR). The possibility of T. vivax transmission by colostrum was assessed by feeding six neonates born of serologically negative goats using colostrum from infected goats. Peripheral blood from neonates was collected daily for thirty days to assess the T. vivax presence through the examination of Giemsa-stained smears of leukocyte layers with the buffy coat technique (BCT) and by PCR. The results of a direct examination of colostrum were negative, but PCR confirmed the presence of T. vivax DNA in all infected goats. Additionally, lactogenic transmission by colostrum was not demonstrated once both BCT and PCR of neonate peripheral blood were negative.

The objective of this study was to describe the clinical and pathological aspects of diseases of the digestive system in agoutis (Dasyprocta leporina Linnaeus, 1758) diagnosed by the “Laboratório de Patologia Veterinária” (Veterinary Pathology Laboratory) of the “Universidade Federal Rural do Semi-Árido” (UFERSA), from January 2018 to February 2020. During the study period, necropsy and a survey of the clinical history of 27 agoutis were performed, 25.93% (7/27) of which were diagnosed with digestive system diseases. The percentages of digestive tract diseases among the diagnosed were: acute carbohydrate overload (11.12%), gastric ulcer (7.41%), gastric volvulus (3.70%), and intestinal volvulus (3.70%). Studies on the occurrence rate of these diseases, as well as the description of their clinical and anatomopathological aspects, may serve as a basis for guiding the appropriate management in the breeding of these animals.