The Houston toad (Anaxyrus [Bufo] houstonensis) is protected under the U.S. Endangered Species Act and is endemic to east central Texas. Since 2007, the Houston Zoo Inc. participated in Houston toad recovery through captive breeding, re‐introduction and maintenance of a captive assurance colony. During 2012 and 2013, the zoo's Houston toad colony experienced increased morbidity and mortality attributed to dermatitis of various aetiologies. An 8‐month time period, from September 2012 through April 2013, was selected to evaluate disease aetiology, treatments administered and success of therapy. A total of 248 toad records were reviewed. During this time, 52 toads that died with dermatitis associated with a fungal or bacterial aetiology or a combination of both were included in the review. Toads that survived (n = 196) had been treated with either oral enrofloxacin (10 mg/kg once daily), itraconazole baths (0.01% solution for 10–15 minutes once daily), enhanced nutrition or a combination of these therapies.
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