Melanotan-II is a potent initiator of erections in men with psychogenic erectile dysfunction and has manageable side effects at a dose of 0.025 mg./kg.

In a controlled trial the effect of traditional Chinese acupuncture v. placebo acupuncture was evaluated in 18 patients with chronic tension headache (mean disease duration 15 years). All patients suffered from daily or frequently recurring headache, the intensity of which was recorded by the patient over a period of 15 weeks. Each patient was treated by traditional Chinese acupuncture as well as by placebo acupuncture in a cross-over design following randomization. Each period of treatment comprised six treatments. Traditional Chinese acupuncture was found to be significantly more pain-relieving than placebo acupuncture, according to the pain registration of the patients themselves. The pain reduction was 31%. Acupuncture is therefore found to be a reasonable treatment for chronic tension headache.

In a double-blind controlled trial the effect of traditional Chinese acupuncture versus placebo acupuncture was evaluated among 17 patients (8 females and 9 males, mean age 45.7 years) with chronic (mean disease duration 5.3 years) unilateral tinnitus. None of the patients had any treatable otological disease. All patients suffered from daily tinnitus, the intensity of which was recorded by the patients themselves every day during a period of 15 weeks. Each patient was treated by traditional Chinese acupuncture as well as placebo acupuncture following randomization (Figure 1). Each period of treatment comprised 2 treatments a week for 3 weeks. Throughout the whole investigation a period effect was recorded, insignificant in the acupuncture-placebo group, but significant in the placebo-acupuncture group (Friedman analysis of variance) (Table 4). There was no significant difference between traditional Chinese acupuncture and placebo (Wilcoxon test, P greater than 0.05, one-tailed). There was no relation between the patients' subjective statements and the results of sound balance measurements as an objective standard of tinnitus (Spearman test).

SYNOPSIS In a controlled trial the effect of traditional Chinese acupuncture versus placebo acupuncture was evaluated in 16 patients with chronic facial pain (13 atypical facial pain, 2 atypical and I typical trigeminal neuralgia). All patients suffered from daily pain, the intensity of which was recorded by the patients over a period of 16 weeks. Each patient was treated by traditional Chinese acupuncture as well as placebo acupuncture in a cross‐over design following randomization. Each period of treatment comprised 10 treatments during two weeks of hospitalization. Traditional Chinese acupuncture was found to be significantly more pain‐relieving than placebo acupuncture according to the pain registration of the patients themselves and to their subjective preferences.

Eleven patients with essential hypertension were treated with hydrochlorothiazide/KCl for three months. A significant fall in total blood volume, exchangeable sodium and blood pressure could be demonstrated both after one to two weeks and after three months of treatment, while a fall in serum sodium and body weight was only significant after one to two weeks of treatment. Thus, hypovolemia may, perhaps, be the explanation for the antipressor effect of thiazide even after three months of treatment.

Melanotan-II is a potent initiator of erections in men with psychogenic erectile dysfunction and has manageable side effects at a dose of 0.025 mg./kg.

EEGs of 42 patients with herpes zoster and 6 with herpes zoster-associated encephalitis were studied to characterize the nature and prevalence of EEG abnormalities in apparently uncomplicated herpes zoster. Thirty-one percent of herpes zoster patients had EEG changes with reduced rhythm frequency ranging from 7 to 2 Hz activity. Frontotemporal localization was observed in 54% of the abnormal EEGs. When compared to EEG in herpes zoster associated encephalitis, the findings were qualitatively the same, but tended to be more severe in the encephalitis cases. No effect of acyclovir on the EEG could be demonstrated.

Antipressor treatment with guanethidine for 8 to 14 days produce a significant average increase in blood volume and exchangeable sodium of 382 ml ( 8 . 5 % ) and 210 mEq (7%), respectively.Subsequent supplementary treatment with hydrochlorothiazide resulted in a normalization of the above-mentioned parameters both during short-term and long-term management.It is proposed that these effects are of importance for the continued hypotensive effect of the thiazides.Acts med. scand. 186 17 -692998