To allow an exchange of measurements and criteria between different electrocardiographic (ECG) computer programs, an international cooperative project has been initiated aimed at standardization of computer-derived ECG measurements. To this end an ECG reference library of 250 ECGs with selected abnormalities was established and a comprehensive reviewing scheme was devised for the visual determination of the onsets and offsets of P, QRS, and T waves. This task was performed by a group of cardiologists on highly amplified, selected complexes from the library of ECGs. With use of a modified Delphi approach, individual outlying point estimates were eliminated in four successive rounds. In this way final referee estimates were obtained that proved to be highly reproducible and precise. This reference data base was used to study measurement results obtained with nine vectorcardiographic and 10 standard 12-lead ECG analysis programs. The medians of program determinations of P, QRS, and T wave onsets and offsets were close to the final referee estimates. However, an important variability could be demonstrated between measurements from individual programs and mean differences from the referee estimates amounted to 10 msec for QRS for certain programs. In addition, the variances of all programs with respect to the referee point estimates were variable. Some programs proved to be more accurate and stable when the data from high-vs low-noise recordings were analyzed. Average Q wave durations calculated from ECGs for which programs agreed on the presence of a Q or QS wave differed by more than 8 msec in several program-to-program comparisons. Such differences may have important consequences with respect to diagnostic performance. Various factors that might explain these differences have been determined. The present study demonstrates that to allow an exchange of results and diagnostic criteria between different ECG computer programs, definitions, minimum wave requirements, and measurement procedures urgently need to be standardized.Circulation 71, No. 3, 523-534, 1985. DURING the last decade rapid growth has occurred in computer electrocardiographic (ECG) processing.1-3 At present, however, no standards for quantitative ECG analysis exist. There is a lack of agreement on The authors academic affiliations are listed in the Common Standards for Quantitative Electrocardiography (CSE) organizational structure that appears before the references.
Purpose -To provide some theoretical considerations concerning information literacy so as to contribute to a theoretically informed point of departure for understanding information literacy and to argue that to be an information literate person is to have knowledge about information sources and that searching and using them is determined by an insight into how knowledge is socially organized in society. Design/methodology/approach -Using concepts from composition studies that deal with the question of what a writer needs to know in order to produce a text, the paper outlines some ideas and key concepts in order to show how these ideas and concepts are useful to our understanding of information literacy. To demonstrate how information-literacy is to have knowledge about information sources and that searching and using them is determined by an insight into how knowledge is socially organized in society, the paper takes a point of departure in Habermas' theory of the public sphere. Findings -Concludes that information seeking competence is a sociopolitical skill, like reading and writing skills, connected to human activity. Searching for documents in information systems is a complex and sociopolitical activity. As an expression of human activity we might say that searching for documents and reading and writing constitutes each other. The genre knowledge necessary in reading and writing does also apply when seeking information in systems of organized knowledge as the forms of information determine what can be expected and found in these systems. Information literacy covers, then, the ability to read society and its textually and genre-mediated structures. Information literacy represents an understanding of society and its textual mediation. Research limitations/implications -Locating an understanding of information literacy in a broader discursive framework requires us to rethink our hitherto concepts and understandings of information literacy as socio-political skills and not mere technical search skills Originality/value -Rarely is information literacy discussed and understood from social-theoretical perspectives. This article illuminates how an analysis of information literacy from the perspective of the theory of the public sphere can open up for an understanding of information literacy socio-political skills. Thus, the article has contributed with a new interpretation of information literacy.
Nineteen patients with L-DOPA treated parkinsonism involving depressive symptoms, the therapeutic effect of nortriptyline was compared to placebo in a controlled trial. The depressive and neurological symptoms were evaluated by rating scales. Nortriptyline had a clinical significant effect with regard to the depressive symptoms, whereas the neurological parameters were unchanged. The authors suggest the depression in Parkinson's disease to be of both reactive and endogenous origins.
This article argues that search engines, algorithms, and databases can be considered as a way of understanding deep mediatization. They are embedded in a variety of social and cultural practices, and as such, they change our communicative actions to be shaped by their logic of archiving, ordering, and searching. I argue that, increasingly and in particular ways, search engines, algorithms, and databases shape our everyday communicative actions as they make us think, internalize, and act along the lines of their particular modes of communication action. After having briefly reviewed recent trends in mediatization research, the argument is discussed and unfolded in between the material and social constructivist-phenomenological interpretations of mediatization. In conclusion, it is discussed how deep this form of mediatization can be taken to be.
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