An exact solution to the moving boundary problem with fractional anomalous diffusion (in time) in drug release devices is presented by means of fractional Green's function and Wright function in this paper. The result given by this paper coincides with the known semi-empirical Ritger-Peppas' formula in controlled drug release system [4]. For convenience of use, an approximate expression of the amount of drug released from polymeric matrix with high accuracy is given out at the end of the paper.

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