Measurements of nuclear magnetic relaxation times for protons of water in living skeletal frog muscle show the transverse relaxation time, T(2), increases when a muscle contracts isometrically. This result and other experimental data suggest that a fraction of the intracellular water molecules have restricted rotational freedom and that this fraction decreases when contraction occurs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.