Attentional biases are known to play a contributing, and perhaps even causal role in the etiology of anxiety and other negative affective states. The prevalence of anxiety disorders in the older cohort is growing, and there are both theoretical and empirical reasons to suspect that age-related factors could moderate attentional bias effects in the context of late-life anxiety. The current study included one of the most widely-used measures of attentional bias, the dot-probe task (Mathews & MacLeod, 1985). Participants were older adults who were either nonanxious or diagnosed with generalized anxiety disorder. The patient subsample also completed cognitive behavior therapy (CBT) or an equivalent wait list condition, after which the dot probe was administered a second time. Results showed that clinical anxiety had no particular importance for the deployment of attention, casting doubt on the universality of biased attention in older anxiety patients. Although there were no maladaptive biases detected toward either threat or depression words at pretreatment, there was nevertheless a marginally significant differential reduction in bias towards threat words following CBT. This reduction did not occur among those in the wait list condition. Implications are discussed.
questionnaire. Diabetes control was defined as Hb1Ac ≤ 7%. Results: The majority of the sample were male (55%) and overweight ). 20.4% of T2DM patients had a history of laboratory-confirmed hypoglycemia. In total, 59% had HbA1c > 7%. The mean age was 60 and the mean T2D duration was 10 years. The mean QoL score of the total sample was -3.1± 1.9, the mean score of non-hypoglycemic patients was -3.05 ± 2.0 while the respective score of hypoglycemic patients was -3.26 ±1.8, (p≤ 0.005). Similar results were observed in the group of controlled patients and uncontrolled patients, who scored -2.73±1.7 and -3.33±1.9, respectively (p≤ 0.005). Comparable results were identified in the majority of the ADDQoL-19 instruments' dimensions. According to the logistic regression analysis the majority of the ADDQoL-19 dimensions were significantly affected by hypoglycemia, as well as by high levels of HbA1c. ConClusions: The study confirmed that the QoL of Greek T2D patients is negatively affected by hypoglycemic events and the level of the disease control. In T2D, treatment should attain good glycemic control without debilitating hypoglycemic episodes, which compromise patients' QoL. PDB138Hypoglycemia (Hypo) is a common adverse effect of type 2 diabetes (T2D) therapy. Hypo has a negative impact on health care resources and quality of life (QoL) and can affect compliance and T2D control. objeCtives: To estimate the impact of Hypo on the QoL as well as its prevalence on T2D patients in Greece. Methods: A cross-sectional epidemiological study was conducted in 6631 patients with T2DM. Hypo events with different treatment regimens, T2D control rates and QoL were assessed. Hypo episodes were defined as laboratory-confirmed (< 70 mg/dl) symptomatic events. QoL was measured using the patient-administered ADDQoL-19
stop thinking about your problems?" The item "how much have you looked forward to things with enjoyment?" was changed to "how much of the time did you feel enjoyment?", and "how much have you felt useful?" was revised to read "how much of the time did you feel useful?" CONCLUSIONS: When translatability assessment is conducted prior to the finalization of a new measure, language changes can be implemented that will facilitate translation and cross cultural adaptation. When difficulties are encountered that may not warrant changes on their own, results from translatability assessments can also be useful in adding awareness and greater weight to other aspects of item structure that might need to be altered to improve the integrity and quality of the measure.
teen of the most disabling conditions as reported by the Centers for Disease Control were also collected. Overall work and activity impairment estimates were calculated for both the full sample and each of the nineteen diagnoses. Results: In total, 50.7% of survey respondents were employed and provided information with respect to their work impairment; all respondents regardless of employment reported their activity impairment. These adults were an average 44.20 years old (SD= 13.52) and 52.6% were male. The mean level of absenteeism, presenteeism, overall work impairment, and activity impairment was 3.49%, 12.91%, 15.01%, and 22.08%, respectively (SDs= 13.88%, 21.98%, 24.96%, and 28.33%, respectively). The highest levels of overall work impairment were observed for patients with AIDS (42.7%), broken bones (36.6%), and hernia or rupture (32.8%) whereas the highest levels of activity impairment were observed for patients with a hernia or rupture (53.9%), kidney problems (48.5%), and back or spine problems (47.5%). ConClusions: These results help to provide some context for work and activity impairment by providing estimates for the overall population as well as for nineteen separate disease states/conditions.
A617 A retrospective, cross-sectional analysis of Brazil National Health and Wellness Survey data was conducted. Economic outcomes included work productivity and activity impairment (past 7 days) and self-reported healthcare use (past 6 months). Humanistic outcomes included Health-related quality of life (HRQoL) using SF-12v2 or SF-36v2 (4-week recall version), and self-reported psychological complaints (past 12 months). Adult patients currently treated for CU were matched 1:4 to controls (never experienced CU) by survey year, age, sex, private insurance and socioeconomic status. Generalized linear models were conducted to compare the patients and matched controls, adjusting for race, income, smoking, obesity, and other comorbidities, using distributions and link functions appropriate for each outcome. Results: Among the patients currently treated for CU (N= 127) and matched controls (N= 508), 80.3% and 78.9% respectively were in labor force (p= 0.73). Employed patients reported significantly higher presenteeism (33.9% vs 21.0%), and overall work impairment (39.1% vs 25.9%); patients also reported higher activity impairment (35.5% vs 23.7%) relative to controls (all p< 0.01). Mean healthcare practitioner (9.7 vs 5.0), emergency room (1.32 vs 0.63) and allergist visits (0.54 vs 0.07) were higher in patients compared to controls (all p< 0.01). Patients had worse HRQoL, including lower mental (5 points) and physical (2.5 points) component summary scores (both p< 0.01), lower (0.06 points) health utility scores (p< 0.001), and were more likely to report anxiety (adjusted odds ratio [OR] = 2.7) and sleep difficulties (OR= 2.2) than controls (both p< 0.001). ConClusions: CSU is likely to impose substantial economic and humanistic burden in Brazilian adults with high impact on patients' HRQoL and on society.
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