This paper presents an update on the carcinogenic effect of formaldehyde. First, generalities of its chemical composition are considered, followed by the description of some of its uses, both in the industry and in health institutions, as well as an account of the risk to which the general population is exposed, in particular health personnel, as a result of prolonged exposure to this chemical component. Emphasis is placed on the concentration of formaldehyde in everyday life and in the workplace, while the guidelines of decree 1477 of August 5, 2014, issued by the Ministry of Labor of Colombia, on occupational exposure to this chemical are analyzed to demonstrate that this decree does not consider the already known carcinogenic effects of formaldehyde, widely supported by scientific evidence, thus leaving a void for both occupational prevention and labor legislation.
Abstract-A series of coagulometers have been developed with the aim of making easier the measurement of coagulation times. A phenomenon that emerges as an alternative for the development of these devices is the use of dynamic laser speckles. It is based on the analysis of time variations of a speckle pattern produced by interference of multiple coherent wavelets scattered by the sample. We present the results of applying correlation analysis to dynamic speckle produced by samples of capillary blood clotting without using any reactive. We also propose a numerical model which describes the obtained curves and a method for measuring coagulation time from this analysis.
Speckle technique is based on the light intensity distribution randomly formed when a laser light is reflected on a rough surface, creating a pattern of illuminated grains (constructively) and dark (destructive) on scales of 1 µm. When the samples are displaced or deformed, the speckle pattern is altered. In this paper we present speckle patterns obtained from samples of gastric mucosa that is physically altered for the carcinogenesis process. Biopsies were studied with different diagnoses and were grouped according to the characteristics of speckle patterns. Speckle patterns were obtained by illuminating the samples with green laser. Morphological parameters of the speckle patterns reveal existence of 3 descriptors: the average grain size, hydraulic radius and the radio of the Weddel disc, which showed a high, intermediate and low value. The comparison shows agreement between the histopathological diagnosis and the values obtained by the speckle technique, making this technique emerge as a new classification system for quantitative diagnosis of precancerous lesions.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.