Evaluation and analysis of 478 cases of carcinoma of the oral cavity treated from 1947 through 1970 shows a significant improvement in radiotherapy in the supervoltage (Co60) era. Survival in the early stages of disease (I and II) improved in the supervoltage era but not in the later stages of disease (III and IV). Results with combined therapy for advanced disease showed no significant difference from that of single mode therapy, whether with radiotherapy or with surgery in the supervoltage era.
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