Source: Bharadwaj SK, Bhat V. Therapeutic hypothermia using gel packs for term neonates with hypoxic ischaemic encephalopathy in resource-limited settings: a randomized controlled trial [published online ahead of print March 6, 2012]. J Trop Pediatr. PICO Question: Among term neonates <6 hours old with hypoxic-ischemic encephalopathy in a resource-limited setting, does whole body cooling using gel packs reduce the risk of death or developmental delay at 6 months as compared with infants receiving usual care? Question type: Intervention Study design: Randomized controlled AAP Grand Rounds™ is published monthly
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