Purpose of our study was to investigate how changing levels of testosterone in the blood and parameters spermogram in infertile men with hypothyroidism, depending on the presence or absence of hypercholesterolemia. We observed 49 infertile men aged 23–44 years, patients with primary hypothyroidism and 15 healthy men of the same age who was absent thyroid disease and disturbance of spermatogenesis (control group). Hypothyroidism patients were divided into two groups: those with a critical level of cholesterol (> 5,2 mmol/l), and patients with lower blood cholesterol concentrations. It was found that in infertile men with primary hypothyroidism, there is an increase in total cholesterol in the blood that are associated with excess weight associated body. Hypercholesterolemia increases the frequency of non-compliance with the level of testosterone in the blood and reduce the number of sperm in the ejaculate of men with pathospermia with hypothyroidism. The increase in blood cholesterol levels in men with infertility hypothyroidism did not significantly affect the performance posttesticular sperm maturation, such as their mobility and vitality.
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