Dynamics of magnetic vortex core switching in nanometer-scale permalloy disk, having a single vortex ground state, was investigated by micromagnetic modeling. When an in-plane magnetic field pulse with an appropriate strength and duration is applied to the vortex structure, additional two vortices, i.e., a circular-and an anti-vortex, are created near the original vortex core. Sequentially, the vortex-antivortex pair annihilates. A spin wave is created at the annihilation point and propagated through the entire element; the relaxed state for the system is the single vortex state with a switched vortex core.

Dynamic response of the vortex magnetization in multilayered magnetic nanopillars to the spin-polarized current pulse has been investigated numerically. The equilibrium magnetization configurations in both magnetic layers are the vortex states with single magnetization cores at the disk center. It was found that the chirality of the vortex state in magnetic free layer can be controllably switched by applying current pulse with appropriate amplitude, polarity, and duration. The critical current density required for the chirality switching is found to be on the order of 108A∕cm2.

We investigated the influence of the magnetic field pulse parameters and the size of the Fe element to the vortex core switching by micromagnetic modeling. When the magnetic field pulse with an appropriate strength and duration is applied to 30nm thick Fe circular disks with diameters between 100nm and 1μm, the vortex configuration is perturbed away from the equilibrium state, and the circular symmetric distribution of the in-plane magnetization around the vortex core deforms. This leads to the creation of a new vortex core with the opposite polarity and an antivortex. With increasing time, the vortex-antivortex pair annihilates. As a result of the annihilation, a single vortex core with opposite polarity remains and a vortex core switch is realized. The process of core switching, however, strongly depends on the amplitude and duration of the magnetic pulse.

This paper proposes a new hypothesis for Alzheimer’s disease (AD)—the lipid invasion model. It argues that AD results from external influx of free fatty acids (FFAs) and lipid-rich lipoproteins into the brain, following disruption of the blood-brain barrier (BBB). The lipid invasion model explains how the influx of albumin-bound FFAs via a disrupted BBB induces bioenergetic changes and oxidative stress, stimulates microglia-driven neuroinflammation, and causes anterograde amnesia. It also explains how the influx of external lipoproteins, which are much larger and more lipid-rich, especially more cholesterol-rich, than those normally present in the brain, causes endosomal-lysosomal abnormalities and overproduction of the peptide amyloid-β (Aβ). This leads to the formation of amyloid plaques and neurofibrillary tangles, the most well-known hallmarks of AD. The lipid invasion model argues that a key role of the BBB is protecting the brain from external lipid access. It shows how the BBB can be damaged by excess Aβ, as well as by most other known risk factors for AD, including aging, apolipoprotein E4 (APOE4), and lifestyle factors such as hypertension, smoking, obesity, diabetes, chronic sleep deprivation, stress, and head injury. The lipid invasion model gives a new rationale for what we already know about AD, explaining its many associated risk factors and neuropathologies, including some that are less well-accounted for in other explanations of AD. It offers new insights and suggests new ways to prevent, detect, and treat this destructive disease and potentially other neurodegenerative diseases.

We report on the development of a new magnetic microscope, time-resolved near-field scanning magneto-optical microscope, which combines a near-field scanning optical microscope and magneto-optical contrast. By taking advantage of the high temporal resolution of time-resolved Kerr microscope and the sub-wavelength spatial resolution of a near-field microscope, we achieved a temporal resolution of ∼50 ps and a spatial resolution of <100 nm. In order to demonstrate the spatiotemporal magnetic imaging capability of this microscope, the magnetic field pulse induced gyrotropic vortex dynamics occurring in 1 μm diameter, 20 nm thick CoFeB circular disks has been investigated. The microscope provides sub-wavelength resolution magnetic images of the gyrotropic motion of the vortex core at a resonance frequency of ∼240 MHz.