What are the novel findings of this work? In pregnancies with early-onset fetal growth restriction and antegrade umbilical artery flow, soluble fms-like tyrosine kinase-1/placental growth factor (sFlt-1/PlGF) ratio at diagnosis is associated with the time interval to delivery. What are the clinical implications of this work? Determination of sFlt-1/PlGF ratio in pregnancies with early-onset fetal growth restriction and antegrade umbilical artery flow may be helpful in planning surveillance, corticosteroid administration and outpatient vs inpatient management.
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