The present study was performed on 153 Iraqi cow buffaloes, suffered from ovarian inactivity after 60 days from calving, in Babylon province in period from November 2012 to August 2013. The affected animals were divided into four groups randomly according to the hormonal treatment regime, 48 cow buffalo treated with 1000 I.U/I.M of PMSG in one does in day 60 postpartum, which represents the 1 st group, while the 2 nd group include 45 cow buffalo treated with 0.021mg/I.M of GnRH (Receptal) in one does in day 60 postpartum, but the 3 rd group (36 cow buffaloes) treated with hCG 1500 I.U/I.M in a single dose also after 60 days postpartum, while 4 th group (24 cow buffalo) was represented the control group(without treatment). The response animals for different hormonal treatment were 87.2%, 80%, 69.4% and 54.1% for the 1 st , 2 nd , 3 rd and 4 th group respectively. The 1 st group which treated with PMSG give higher significant differences (p<0.01) compared with other groups, also the 2 nd group (treated with GnRH) record significant differences (p<0.01) compared with 3 rd and 4 th group. The duration of response also record higher significant differences (p< 0.01) between 1 st and 2 nd group compared with 3 rd and 4 th group, while the number of services per conception was no different between all groups, but the pregnancy rate record superior significant differences (p<0.01) for the 1 st group compared with other groups and reached to 85% but the 4 th group (control group) record low ratio compared with treated groups. Finally the days open was recorded superior significant differences between 1 st and 2 nd group compared with 3 rd and 4 th group, also 4 th group record long postpartum period (175.82± 13.56 days). They concluded in this study that the hormonal treatment still an important method to treated the ovarian inactivity and this fact depends on the many reproductive parameters which involve the rate of response animals, duration of response, number of services per conception, pregnancy rate and days open.
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