In 20 iron deficient patients and 21 normal controls the activity of the enzyme δ-ALA dehydratase of erythrocytes was assayed. In addition the urine porphyrins and porphyrin precursor excretions were measured. It was found that in sideropenic patients the erythrocyte δ-ALA dehydratase activity was almost constantly higher than in normals; the difference of the mean values being statistically significant (p < 0.005). A significant diminution of δ-ALA (p < 0.0025) urine excretion was observed, whereas the urine excretion of PBG, CP and UP was found within the normal limits. The results are compared to those reported by other authors.

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SUMMARY In a study of the lipoprotein pattern in multiple myelomatosis electrophoresis on agarose gel showed abnormal lipoproteins, named paralipoproteins (p-Lp), in 24 out of 30 normolipidaemic patients. These paralipoproteins were grouped according to their mobility into one or another of the following types: (1) p-Lp1 with a mobility identical with that of y-globulin, (2) p-Lp2 with a mobility between that of /-and y-globulin, (3) p-Lp3 with a mobility identical with that of /-globulin. On ultracentrifugation the abnormal lipoproteins were found to have a density above 1-063 g/ml.

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