Antioxidant Properties of Benzimidazoles 5-Hydroxybenzimidazoles have been shown to possess marked antioxidant properties. By contrast benzimidazole and its 2-alkyl derivatives have no direct antioxidant activity, but appear to function as retarders of metal-catalyzed autoxidations.As part of a study of oxidation of heterocyclic molecules related to their biological properties, oxidations of some benzimidazoles have been examined (Cole et al, 1974).Relevant to this work the ability of these compounds to function as antioxidants has been evaluated, leading to the discovery of a novel class of active antioxidants. EXPERIMENTAL SECTIONBenzimidazole and its 2-alkyl derivatives were prepared by standard methods (Phillips, 1928); 5-hydroxybenzimidazoles were formed by Udenfriend oxidation of the parent compounds (Udenfriend et al., 1954). All compounds were shown to be pure by thin-layer chromatographic (tic) analysis (Cole et al., 1973). Squalene, vacuum distilled and filtered through grade I alumina under an atmosphere of nitrogen, was used as the substrate, for accelerated oxidations (in triplicate) at 60°under 1 atm pressure of oxygen.
. 1992. Edible land snail production under natural climatic conditions in Nova Scotia. Can. J. Anim. . One thousand two hundred and fifty land snails were divided randomly among 25, 1.5-m x 0.9-m x 1'5-m cages wrapped in a nylon screen and chicken wire to prevent the snails fiom escaping and to protect them from predators. The cages were placed in a shaded area on the southeastern edge of a white clover field and randomly divided into five nutritional treatments with each treatment replicated five times.The snails were fed with natural vegetation, lettuce and oyster shells, lettuce alone, oat bran, or white clover in treatments 1,2, 3,4, and 5, respectively. A digestibility trial on lettuce and white clover was also carried out. content was measured and they were then stored.
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