Background: Preterm low birth weight (PLBW) is one of the causes of infant mortality and morbidity. Most of the studies have indicated the periodontal-systemic interlink. The association of periodontal pathogen on pregnancy outcome still stands inconclusive. The aim of the study was to detect the prevalence of Porphyromonas gingivalis in umbilical cord blood of new-born infant and correlate the same pathogen in subgingival plaque of pregnant women and to determine the adverse pregnancy outcomes and also to determine the correlation between periodontitis and the association of P. gingivalis in preterm birth/low birth. Materials and Methods: The present study included 130 pregnant participants in their full-term and preterm delivery with periodontitis. Periodontal disease was diagnosed clinically using gingival index, pocket depth, plaque index, and clinical attachment level. Umbilical cord blood samples and plaque samples collected using Gracey curette were subjected to culture for the detection of P. gingivalis. The results were subjected to the statistical analysis using the SPSS software. Results: The comparison of P. gingivalis in umbilical cord blood and plaque between preterm and full-term group was found to be significantly increased in preterm group. A statistically significant difference was also seen for the clinical parameters between the two groups, with increased values seen in case of preterm labor. Odd's ratio on the comparison of prevalence of periodontitis among full term and preterm group was statistically significant in preterm birth as compared with full-term birth. Conclusion: The study results showed statistically significant association of P. gingivalis with PLBW. Periodontal disease significantly affects the adverse pregnancy outcome.
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