mononuclear cells and cultured with IL-2 and other cytokines for 2 weeks. The purity of lymphocytes was assessed by flow cytometric analysis, and only the CD3 À CD56 + cells greater than 70% were used. The adverse effects, laboratory tests, overall survival were assessed. Results: No serious adverse effects, laboratory abnormalities were identified as related to the treatment of NK cells. Six patients were alive in the follow-up period of 2 e 8 months. There was no graft-versus-host disease in all 6 patients during follow-up.
Conclusion:In conclusion, we have demonstrated for the first time to our knowledge that NK cells from sibship with the same blood type can be used safely as adoptive immunotherapy for the treatment of HCC recurrence after liver transplantation.
Hepatic atrophy caused by PBL is associated with increased expression of genes known to promote tumor growth. These host events represent a possible explanation for the tumor progression after portal occlusion and require further evaluation.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.