The chemical studies and antimicrobial activity of n-hexane leaf extract of Corymbiatorelliana was evaluated for medicinal importance. The phytochemical constituents present were steroids, tannins, cardiac glycosides alkaloids and terpenes. The result of sodium fussion test revealed the presence of Phosphorus Nitrogen and Chlorine. The Column Chromatography gave several fractions that were pulled together by Thin Layer Chromatography based on their Rf values, colours and resolutions on different solvent systems. GC-MS was used to identify compounds like: Hexadecanoic acid methyl ester, 9,12-Octadecadienoic acid methyl ester, 2,2,4,4-tetramethyl-1,3-cyclobutanediene, Pentadecanoic acid-14-methyl methyl ester, Hexadecanoic acid-2-hydroxyl propyl ester, 2(4H)-Benzofuranone-5,6,7,7a-tetrahydro-4,4,7a-trimethyl and many others. Antimicrobial screening was carried out on Escherichia coli, Staphylococcus aureus and Aspergillus niger using the agar well diffusion technique. The result shows that the extract exhibit antimicrobial activity with zones of inhibition in diameter. These results show that the plant exhibit antimicrobial activity and possess pharmacological characteristics, which could be applied in the production of potent drugs.
Chemical modifications of lignocelluloses materials are advance development that are fast and convenient to convert the low value woody residues to create channels for controlling the release of organic manure to proffer solutions to farmers in the increasing soil acidity, rapid weed's growth, soil infertility and food scarcity. The study investigates the physic-chemical parameters, and the effect of immobilized nitrogenous bases on oxidized sawdust for controlling Striga hermonthica in the sorghum field. The results indicate that the moisture content increases with increase particle size as water absorption capacity increases with time and size, thereby, ash content decrease with increase size. The control, oxidized and immobilized sawdusts were analyzed using FT-IR and it was clear that pretreated sawdust of 0.08-0. 10M KIO4 oxidized the exposed hydroxyl groups of the lignocelluloses material to the carbonyl group but were unable in 0.04-0.06M KIO4. Likewise, the absorption bands showed that the nitrogenous bases were incorporated while carbonyl absorptions were still observed. The effect of immobilized Dimethylamine concentrations on gradual release on sorghum grows progressively with the absence of S. hermonthica while aniline grows faster than Dimethylamine at 0.5-1.0M then diminished at 1.5M than Dimethylamine. The application of immobilized amines on the sorghum field showed that this invention would enhance sorghum productivity through striga control.
Crinum zeylanicum (L.) of the family Amaryllidaceae is one of the medicinal plants that have gained ancient-to-date popularity in the healing of skin diseases, bone fracture and other tropical illnesses in traditional medicine practices. The grounded bulb was extracted successively using n-hexane, ethyl acetate, methanol and water. The raw sample and the successive extracts were evaluated for alkaloids, flavonoids, saponins, steroids and tannins contents using specific standard gravimetric methods for each component. Correlation analysis of the components was also carried out. The quantitative determinations revealed the range of the bio-components as saponins (37.20-13.08%,), alkaloids (22.14-4.62%), Tannins (19.47-2.79%), Flavonoids (15.32-0.08%) and Steroids (10.49-0.72). The correlation coefficient analysis at 5% identified high negative correlation between saponins and steroids at (-0.921) as the most significant value (p=0.026), likewise alkaloids and saponins, alkaloids and tannins, flavonoids and saponins, flavonoids and tannins, steroids and tannins but statistically insignificant. It however, revealed high positive correlation of alkaloids and steroids (+0.872) at insignificant value (p=0.055) and such other correlations in this study are alkaloids and flavonoids, flavonoids and steroids, saponins and tannins. At 95% confidence interval of the differences in the paired components, showed that alkaloids and steroids, flavonoids and saponins, saponins and steroids, saponins and tannins are statistically significant (p=0.009- 0.012) while others are insignificant (p-0.057-0.978). These results indicated that the bulb contained essential medicinal components suitable for health benefits and considered a multifaceted plant for curing many types of diseases and illnesses.
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