wir bei den Untersuchungen zu den Apgar-Werten, den arterieUen pH-, pCO2-, pO 2-Werten beider Kollektive. Bei Schwangeren mit Harnweginfekt betrug die perinatale Mortalit/it 3,5% (12 Kinder). Im Vergleiehskollektiv verstarb ein Kind (0,3%). Komplikationen wie Lochialstau, Thrombophlebitiden und Rezidive von Harnweginfekten fanden sich bei Patientinnen mit Harnweginfekt signifikant h/iufiger.Bei graviden Frauen mit Bakteriurie ist also trotz antibiotischer Behandlung und ordnungsgem~il3er Schwangerschaftsbetreuung mit signifikant h/iufigeren Komplikationen als bei Graviden ohne Harnweginfekt zu rechnen. Gerinnung 448. R. E. Zimmermann, J. Babenerd, A. Aszadeh (Miinster und Bremerhaven): Meehanismen der Thromblnwirkung bei der Fibrlnogen/Fibrln-Konverslon
The coagulation cascade can be triggered by an extrinsic or intrinsic signal. The response is a highly complex activation sequence of several serine proteases. This physiological event of hemostasis comprises the activation of the kinin system as well as other plasma constituents. As an expression of the dynamic balance between fibrinogenesis and fibrinolysis plasminogen is activated either by proteases deriving from the blood clotting cascade or by its linkage to the kallikrein kinin system. Inhibitors of the fibrinolytic events have to be directed specifically against serine proteases or they may be used to interact with the substrate fibrin thus its degradation is delayed.
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