The cognitive outcome of three groups of patients, who had undergone surgery for repair of a single ruptured intracranial aneurysm, was evaluated. We assessed performance on tests of executive functions and memory in a group of 15 patients tested at least 3 months after an aneurysm of the anterior communicating artery (ACoA) and in a group of 12 patients tested in the first month after the same pathology. Acute patients were more impaired overall than chronic ones, but the two groups significantly differed on two executive and one memory test. The performance of the ACoA patients was also compared to the performance of a group of 10 patients who had undergone surgery for an aneurysm located on the posterior communicating artery (PCoA) at least 3 months before the examination. Chronic ACoA and PCoA patients significantly differed in two memory and in two executive tests performance, with posterior patients being more impaired than anterior. An unexpected finding was the impairment of semantic memory in ACoA patients.
sellar and parasellar masses blocking inhibitory hypothalamic dopaminergic tonus can produce hyperprolactinemia. one of these conditions, seldom reported, is internal carotid artery aneurysm causing pituitary stalk compression and hyperprolactinemia, the majority of which is related to small increases in serum prolactin levels. the aim of this study is to report the case of a patient with an internal carotid aneurysm and severe hiperprolactinemia. A 72 years old female patient, on oncology follow-up for clinically controlled cervical carcinoma, was evaluated due to worsening chronic headaches. during the investigation, computed tomography and magnetic resonance imaging (Mri) showed a sellar mass associated with high prolactin level (1.403 µg/l) that initially was considered a macroprolactinoma, and treated with bromocriptine. However, subsequent pituitary Mri suggested an internal carotid aneurysm, which was confirmed by an angioresonance imaging of cerebral vessels. on low bromocriptine dose (1.25 mg/day), there was a prompt normalization of prolactin levels with a great increase (> 600 µg/l) after withdrawal, which was confirmed several times, suggesting HPd. We report a patient with internal carotid artery aneurysm with severe hyperprolactinemia never reported before in patients with HPd, and the need for a differential diagnosis with macroprolactinomas even considering high prolactin levels. Massas selares e parasselares podem produzir hiperprolactinemia por bloquear o tônus inibitório hipotalâmico de dopamina. uma destas condições, raramente reportada, é o aneurisma de artéria carótida interna causando compressão da haste hipofisária e hiperprolactinemia, a maioria com pequenas elevações da prolactina. o objetivo deste estudo é descrever o caso de uma paciente com aneurisma de carótida interna e grave hiperprolactinemia. Paciente feminina, 72 anos, em acompanhamento oncológico por carcinoma de colo de útero clinicamente controlado, avaliada por causa da piora de cefaléia crônica. durante investigação, tomografia computadorizada e ressonância magnética (rM) de hipófise mostraram massa selar associada com altos níveis de prolactina (1.403 µg/l), sendo avaliado como macroprolactinoma e tratado com bromocriptina. entretanto, rM subseqüente sugeriu aneurisma de carótida interna que foi confirmado por angiorressonância de vasos cerebrais. em uso de baixas doses de bromocriptina (1,25 mg/dia), houve pronta normalização da prolactina com grande elevação (> 600 µg/l) após a retirada do medicamento, sendo confirmado por várias vezes sugerindo dHH. reporta-se uma paciente com aneurisma de artéria carótida interna com grave hiperprolactinemia, nunca descrita anteriormente em pacientes com dHH, e a necessidade do diagnóstico diferencial com macroprolactinoma, mesmo considerando altos níveis de prolactina. Descritores: Hiperprolactinemia; Aneurisma de artéria carótida interna; desconexão hipotálamo-hipofisária; Prolactinoma; diagnóstico diferencial de tumor hipofisário
experience significantly worse outcomes (MRS >= 3) relative to patients having at least one tooth remaining (OR = 1.11 [0.63, 1.99], p = 0.7). Missing any teeth was not significantly associated with worse outcomes (OR = 1.26 [0.64, 2.45], p = 0.5). Patients who experienced worse outcomes also had more missing teeth (mean = 12 +/-11) on average than those who experienced good outcomes (mean = 10 +/-11, p = 0.066), but this trend is non-significant. Conclusion To our knowledge, this is the first study to quantitatively assess oral health and stroke outcomes. Our retrospective review revealed mixed association between missing teeth and thrombectomy outcomes, however with no statistically significant correlation demonstrated between missing observable (front) teeth and poor outcomes after thrombectomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.