[reaction: see text] Fe(III)-mediated ring opening of cyclopropyl ethers bearing a phenyl-substituted butenyl side chain leads to the generation of beta-keto radicals that undergo 5-exo cyclization followed by a novel cascade sequence resulting in the formation of tricyclic ethers.

We present Lotus; an actuated plant-like device designed to guide the user through breathing exercises. The development of Lotus explores whether IoT devices can aid in the practice of mindfulness and reducing stress. Lotus uses heart rate (HR) monitoring to detect high levels of stress and trigger the start of its guided exercises through the movement of its petals. An initial study proved that Lotus may help users to reduce their stress.

Ring closure reactions Ring closure reactions O 0130New Fe(III)-Mediated Radical Cascade Reactions of Cyclopropyl Silyl Ethers.-Fe(III)-Mediated ring opening of cyclopropyl ethers (III) and (VIII) leads to the generation of β-keto radicals, which smoothly undergo 5-exo cyclization to cyclopentane derivatives with predominant cis-configuration [cf. (V), (VI), (X) -(XII)]. The presence of an α-phenyl substituent in the butenyl side chain of the cyclopropyl ethers, however, leads to a further reaction of the initial β-keto radicals, affording unexpected tricyclic ethers (IX) via a novel radical cascade process. The overall yield and the ratio of tricyclic ether to 5-exo product depends on the relative size of the cyclopropyl substituent. -(BOOKER-MILBURN*, K. I.; JONES, J. L.; SIBLEY*, G. E. M.; COX, R.; MEADOWS, J.; Org. Lett. 5 (2003) 7, 1107-1109; Sch. Chem., Univ. Bristol, Cantock's Close, Bristol BS8 1TS, UK; Eng.) -Mischke 31-044 2003 Ring closure reactions