An FFR of <0.80 is associated with a lack of an adenosine-inducible increase in oxygenation of the dependent coronary territory, while a complete lack of such an increase was best predicted by an FFR of <0.54. Further studies are warranted to identify clinically meaningful cut-off values for FFR measurements and to assess the utility of OS-CMR as an alternative clinical tool for assessing the functional relevance of coronary artery stenosis.

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Oxygenation-sensitive CMR at 1.5T can be used to identify functionally significant coronary artery stenosis, by demonstrating a blunted response to adenosine induced hyperaemia. Image quality remains a limitation.