declined between each age bracket (p,0.015), with LA contractile strain increasing in groups 'b' and 'c' vs group 'a' (p=0.006 and p,0.001, respectively). Conclusion: LA conduit strain is altered early with a compensatory increase in LA contractile strain, whilst LA reservoir strain shows progressive reduction with increasing age. These phasic functional changes are reflected by an early increase in LA PreP volume and subsequent increase in LA min .
the mean reduction in RVSP across all three groups was 8.7% (SD ± 27.8%) (p = 0.00005). Patients with both moderate and severe pulmonary hypertension at baseline had significant mean RVSP reduction of 18% (SD ± 23.7%) (p = 0.0002) and 29.8% (SD ± 20.7%) (p = 0.001) respectively. No significant change was recorded in the mild group.Conclusion: TAVI resulted in statistically significant reductions in pulmonary hypertension in patients with moderate-to-severely elevated pulmonary pressures at baseline.
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