Blood fibrinolytic activity and plasma cortisol concentrations were investigated in 15 patients undergoing upper or lower abdominal surgery under high or low extradural blockade plus general anesthesia. It was found that the initial enhancement of fibrinolysis could be prevented but only in those patients showing impaired cortisol responses. This suggests a common nervous mechanism unrelated to the degree of sensory blockade.
Pigmented villonodular synovitis (PVS) was diagnosed in 25 patients during the period 1950--76. Twenty-two of the patients were re-examined 2--28 years later. Three patients with local affection of tendon sheaths, treated by excision, were all free of symptoms at follow-up. Nineteen patients all with unilateral knee joint affection were divided into two groups according to peroperative findings, 6 localized PVS and 13 diffuse PVS. The 6 patients with localized PVS all had normal knee movement at follow-up, whereas the 13 with diffuse involvement had varying impaired knee mobility.
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