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In this paper we evaluate the suitability of handwriting patterns as potential biomarkers to model Parkinson's disease (PD). Although the study of PD is attracting the interest of many researchers around the world, databases to evaluate handwriting patterns are scarce and knowledge about patterns associated to PD is limited and biased to the existing datasets. This paper introduces a database with a total of 935 handwriting tasks collected from 55 PD patients and 94 healthy controls (45 young and 49 old). Three feature sets are extracted from the signals: neuromotor, kinematic, and nonlinear dynamic. Different classifiers are used to discriminate between PD and healthy subjects: support vector machines, knearest neighbors, and a multilayer perceptron. The proposed features and classifiers enable to detect PD with accuracies between 81% and 97%. Additionally, new insights are presented on the utility of the studied features for monitoring and detecting PD.

The objective of this competition (4NSigComp2010) is to ascertain the performance of automatic off-line signature verifiers to evaluate recent technology developments in the areas of document analysis and machine learning. The current paper focuses on the second scenario, which aims at performance evaluation of off-line signature verification systems on a newly-created large dataset that comprises genuine, simulated signatures produced by unskilled imitators or random signatures (genuine signatures from other writers). Ten systems were evaluated, and some interesting results are presented in terms of accuracy and execution time. The top ranking system attained an overall error of 8.94%. This result interestingly correlates with the top ranking accuracy achieved in a previous signature verification competition at ICDAR 2009.