We have demonstrated the first in-vivo high resolution images of normal punctal and vertical canalicular anatomy using spectral OCT. There is currently no other practical way to accurately image punctal and proximal canalicular morphology in vivo. OCT is a convenient and readily available tool in most eye clinics with resolution ideally suited for imaging of the punctum and proximal canaliculus.
The supervised community-based exercise program implemented in this study was designed to address specific functional needs for individuals with lower limb loss. Each participant experienced clinically meaningful improvements in balance, balance confidence, and walking ability. Clinical relevance The provision of a supervised community-based exercise program, after traditional rehabilitation, provides opportunity to offer a continuum of care that may enhance prosthetic functional ability and active participation in the community for individuals with lower limb amputation.
This experiment investigated the effects of intensity of exercise on excess postexercise oxygen consumption (EPOC) in eight trained men and eight women. Three exercise intensities were employed 40%, 50%, and 70% of the predetermined maximal oxygen consumption (VO2max). All ventilation measured was undertaken with a standard, calibrated, open circuit spirometry system. No differences in the 40%, 50% and 70% VO2max trials were observed among resting levels of oxygen consumption (VO2) for either the men or the women. The men had significantly higher resting VO2 values being 0.31 (SEM 0.01) l.min-1 than did the women, 0.26 (SEM 0.01) l.min-1 (P < 0.05). The results indicated that there were highly significant EPOC for both the men and the women during the 3-h postexercise period when compared with resting levels and that these were dependent upon the exercise intensity employed. The duration of EPOC differed between the men and the women but increased with exercise intensity: for the men 40%--31.2 min; 50%--42.1 min; and 70%--47.6 min and for the women, 40%--26.9 min; 50%--35.6 min; and 70%--39.1 min. The highest EPOC, in terms of both time and energy utilised was at 70% VO2max. The regression equation for the men, where y = O2 in litres, and x = exercise intensity as a percentage of maximum was y = 0.380x + 1.9 (r2 = 0.968) and for the women is y = 0.374x - 0.857 (r2 = 0.825).(ABSTRACT TRUNCATED AT 250 WORDS)
In brief: The physiologic responses to running on a treadmill and to running in water while wearing a buoyant vest were compared in seven uninjured runners. Ventilation, oxygen uptake, and respiratory quotient were significantly higher during treadmill running, whereas heart rate and perceived exertion were not significantly different for the two forms of exercise. Water running elicited a 36% lower metabolic cost than treadmill running despite the athletes' efforts to maintain a similar level of exertion. The results suggest that water running may help lessen the rate of deconditioning of injured athletes who must suspend their regular forms of exercise, but they fail to show that the metabolic cost of water running is significantly greater than that of treadmill running.
PurposeDry eye syndrome (DES) causes significant morbidity. Trials of blood-derived products in treatment of the condition show promising results. However, their production is expensive and time-consuming. We investigate fingerprick autologous blood (FAB) as an alternative low-cost, readily accessible treatment for DES.Patients and methodsProspective, non-comparative, interventional case series. In total, 29 eyes of 16 DES patients (2 males and 14 females) from two NHS sites in the United Kingdom. Patients instructed to clean a finger, prick with a blood lancet, and apply a drop of blood to the lower fornix of the affected eye(s), 4 times daily for 8 weeks then stop and review 4 weeks later. Follow-up visits occurred ~3 days, 2, 4, 8 weeks into therapy, and 4 weeks post-cessation. At each visit, visual acuity, corneal staining, Schirmer's test, tear break-up time (TBUT), and ocular comfort index (OCI) were measured, and photographs taken. Results were analysed using Student's paired t-test.ResultsAt 8 weeks, there was improvement in mean Oxford corneal staining grade (3.31 to 2.07 (P<0.0001)), TBUT (5.00 to 7.80 s (P<0.05)), visual acuity (0.08 to 0.01 LogMAR equivalent (P<0.05)), and OCI score (56.03 to 39.72 (P<0.0001)). There was no statistically significant change in Schirmer's test results. Four weeks post-cessation versus immediately after completion of FAB therapy, mean staining grade worsened from 2.07 to 2.86 (P<0.0001). OCI score worsened from 39.72 to 44.67 (P<0.05).ConclusionsIn our limited case series FAB appears to be a safe and effective treatment for DES.
A number of submaximal step tests have been developed to predict maximal aerobic capacity. Because step height may influence biomechanical efficiency and heart rate, step tests based on subjects' stature may more accurately predict maximal aerobic capacity. Eighteen women performed the Queens College step test and a modified Queens College step test. The modified step test was performed with the height of the bench set even with the height of the foot at a knee angle of 90 degrees. Analysis of the data indicated a lower recovery heart rate following this test (p < .05). Further, correlations between maximal aerobic capacity and recovery heart rate for both tests were moderate (r = -.80 and -.75, respectively). Our results suggest that step tests based on subjects' stature do not more accurately predict aerobic capacity than those using a standardized bench height.
TCD monitoring plays an important role in the training and quality control of carotid endarterectomy and helps significantly to reduce the amount of microembolization.
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