A method for the computation of low Reynolds number dynamic blood cell systems is presented. The specific system of interest here is interaction between cancer cells and white blood cells in an experimental flow system. Fluid dynamics, structural mechanics, six-degree-of freedom motion control and surface biochemistry analysis components are coupled in the context of adaptive octreebased grid generation. Analytical and numerical verification of the quasi-steady assumption for the fluid mechanics is presented. The capabilities of the technique are demonstrated by presenting several three-dimensional cell system simulations, including the collision/interaction between a cancer cell and an endothelium adherent polymorphonuclear leukocyte (PMN) cell in a shear flow.
The hydraulics and the mass-transfer behavior of a five-tray, single-bubble-cap, single-downcomer, gas-liquid contactor were studied for use as a gas scrubber. Flooding was not observed at the maximum available liquid and gas flow ratas of 0.32 and 464 L/min, respectively. The maximum liquid entrainment was 33% at a gross liquid flow rate of 0.05 L/min. The Murphree-tray efficiencies for absorption of CO2 (5000 ppm in air) into deirineralized water ranged from 0.14 to 0.74 for volumetric liquid-togas ratios of 4 x 10 _1 J and 2 x 10-4, respectively, for kia values ranging from 0.088 to 0.36 min" 1. 3 0.050 255 2 x 10" 4 4 0.101 255 4 x 10" 4 a Flow rates are given at 25°C and atmospheric pressure, Run 1 was stopped hecause of minor equipment failure.
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