n¼69; p<0.001) and $10 mm polyps (21%, n¼63; p<0.001). The histological features of the polyps #5 mm were predominantly tubular adenomas (TA) (80%, n¼86/107), please see Abstract PWE-110 table 1 for rest of histology. Only 38% (n¼66) of polyps #5 mm were hyperplastic in nature. In polyps #5 mm in size, one TA with high grade dysplasia (0.6%) was seen but no carcinoma compared to 11 (3.6%) carcinomas/high grade dyspasia in $6 mm size polyps (p<0.001). Three cancers were seen, two in polyps $10 mm size and one in the 6e9 mm size. 51% were left sided, 14% were right sided, location not specified in 35%, this difference was not statistically significant. Conclusion In patients who are positive for FHH the incidence of diminutive polyps is considerable and importantly there is a significant proportion of adenomatous polyps. Based on these findings we believe that diminutive polyps should be resected, histologically evaluated and followed-up appropriately.
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