The addition of paclitaxel to best supportive care significantly improved survival and time to disease progression compared with best supportive care in patients with advanced NSCLC and may improve some aspects of QOL.

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This illustrative review depicts the evolving role of magnetic resonance imaging (MRI) in the diagnosis and prognostication of anomalies of the fetal body (here including head and neck, thorax, abdomen and spine). A review of the current literature describing the state-of-theart in antenatal imaging for diagnosis and prognostication of congenital anomalies is coupled with illustrative cases in true radiological planes with viewable 3D video models that demonstrate the potential of post-acquisition reconstruction protocols.Within, we will discuss benefits and limitations of fetal MRI across the breadth of conditions included: from anomaly detection, classification and prognostication as well as defining the role of imaging in the decision to proceed to prenatal intervention. Reference will also be made to the current capabilities of ultrasound and we will explore potential ways in which the two may perform complimentary roles in the future of prenatal imaging.

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