Aims The aim of this study was to estimate the 90-day risk of revision for periprosthetic femoral fracture associated with design features of cementless femoral stems, and to investigate the effect of a collar on this risk using a biomechanical in vitro model. Materials and Methods A total of 337 647 primary total hip arthroplasties (THAs) from the United Kingdom National Joint Registry (NJR) were included in a multivariable survival and regression analysis to identify the adjusted hazard of revision for periprosthetic fracture following primary THA using a cementless stem. The effect of a collar in cementless THA on this risk was evaluated in an in vitro model using paired fresh frozen cadaveric femora. Results The prevalence of early revision for periprosthetic fracture was 0.34% (1180/337 647) and 44.0% (520/1180) occurred within 90 days of surgery. Implant risk factors included: collarless stem, non-grit-blasted finish, and triple-tapered design. In the in vitro model, a medial calcar collar consistently improved the stability and resistance to fracture. Conclusion Analysis of features of stem design in registry data is a useful method of identifying implant characteristics that affect the risk of early periprosthetic fracture around a cementless femoral stem. A collar on the calcar reduced the risk of an early periprosthetic fracture and this was confirmed by biomechanical testing. This approach may be useful in the analysis of other uncommon modes of failure after THA. Cite this article: Bone Joint J 2019;101-B:779–786.

Aims Periprosthetic femoral fractures (PPF) are a serious complication of total hip arthroplasty (THA) and are becoming an increasingly common indication for revision arthroplasty with the ageing population. This study aimed to identify potential risk factors for PPF based on an analysis of registry data. Methods Cases recorded with PPF as the primary indication for revision arthroplasty in the German Arthroplasty Registry (Endoprothesenregister Deutschland (EPRD)), as well as those classified as having a PPF according to the International Classification of Diseases (ICD) codes in patients’ insurance records were identified from the complete datasets of 249,639 registered primary hip arthroplasties in the EPRD and included in the analysis. Results The incidence of PPFs was higher (24.6%; 1,483) than reported in EPRD annual reports listing PPF as the main reason for revision (10.9%; 654). The majority of fractures occurred intraoperatively and were directly related to the implantation process. Patients who were elderly, female, or had comorbidities were at higher risk of PPFs (p < 0.001). German hospitals with a surgical volume of < 300 primary procedures per year had a higher rate of PPFs (p < 0.001). The use of cemented and collared prostheses had a lower fracture risk PPF compared to uncemented and collarless components, respectively (both p < 0.001). Collared prostheses reduced the risk of PPF irrespective of the fixation method and hospital’s surgical volume. Conclusion The high proportion of intraoperative fractures emphasises the need to improve surgeon training and surgical technique. Registry data should be interpreted with caution because of potential differences in coding standards between institutions. Cite this article: Bone Joint J 2021;103-B(4):650–658.

Abstract. Owing to an ageing population, the impact of unhealthy lifestyle, or simply congenital or gender specific issues (dysplasia), degenerative bone and joint disease (osteoarthritis) at the hip pose an increasing problem in many countries. Osteoarthritis is painful and causes mobility restrictions; amelioration is often only achieved by replacing the complete hip joint in a total hip arthroplasty (THA). Despite significant orthopaedic progress related to THA, the success of the surgical process relies heavily on the judgement, experience, skills and techniques used of the surgeon. One common way of implanting the stem into the femur is press fitting uncemented stem designs into a prepared cavity. By using a range of compaction broaches, which are impacted into the femur, the cavity for the implant is formed. However, the surgeon decides whether to change the size of the broach, how hard and fast it is impacted or when to stop the excavation process, merely based on acoustic, haptic or visual cues which are subjective. It is known that non-ideal cavity preparations increase the risk of peri-prosthetic fractures especially in elderly people. This study reports on a simulated hip replacement surgery on a cadaver and the analysis of impaction forces and the microphone signals during compaction. The recorded transient signals of impaction forces and acoustic pressures (≈ 80 µs -2 ms) are statistically analysed for their trend, which shows increasing heteroscedasticity in the force-pressure relationship between broach sizes. TIKHONOV regularisation, as inverse deconvolution technique, is applied to calculate the acoustic transfer functions from the acoustic responses and their mechanical impacts. The extracted spectra highlight that system characteristics altered during the cavity preparation process: in the high-frequency range the number of resonances increased with impacts and broach size. By applying nonlinear time series analysis the system dynamics increase in complexity and demand for a larger minimum embedding dimension. The growing number of resonances with similar level of the transfer function indicates a higher propensity to dissipate energy over sound; the change in embedding dimension indicates a decrease in linearity. The spectral changes as well as the altered dimension requirements indicate either an improved coupling between the bone and the broach or the onset of micro-fractures caused by growing stress levels within the bone.

Owing to an ageing population, the impact of unhealthy lifestyle, or simply congenital or gender specific issues (dysplasia), degenerative bone and joint disease (osteoarthritis) at the hip pose an increasing problem in many countries. Osteoarthritis is painful and causes mobility restrictions; amelioration is often only achieved by replacing the complete hip joint in a total hip arthroplasty (THA). Despite significant orthopaedic progress related to THA, the success of the surgical process relies heavily on the judgement, experience, skills and techniques used of the surgeon. One common way of implanting the stem into the femur is press fitting uncemented stem designs into a prepared cavity. By using a range of compaction broaches, which are impacted into the femur, the cavity for the implant is formed. However, the surgeon decides whether to change the size of the broach, how hard and fast it is impacted or when to stop the excavation process, merely based on acoustic, haptic or visual cues which are subjective. It is known that non-ideal cavity preparations increase the risk of peri-prosthetic fractures especially in elderly people. This study reports on a simulated hip replacement surgery on a cadaver and the analysis of impaction forces and the microphone signals during compaction. The recorded transient signals of impaction forces and acoustic pressures (≈ 80 µs-2 ms) are statistically analysed for their trend, which shows increasing heteroscedasticity in the force-pressure relationship between broach sizes. TIKHONOV regularisation, as inverse deconvolution technique, is applied to calculate the acoustic transfer functions from the acoustic responses and their mechanical impacts. The extracted spectra highlight that system characteristics altered during the cavity preparation process: in the high-frequency range the number of resonances increased with impacts and broach size. By applying nonlinear time series analysis the system dynamics increase in complexity and demand for a larger minimum embedding dimension. The growing number of resonances with similar level of the transfer function indicates a higher propensity to dissipate energy over sound; the change in embedding dimension indicates a decrease in linearity. The spectral changes as well as the altered dimension requirements indicate either an improved coupling between the bone and the broach or the onset of micro-fractures caused by growing stress levels within the bone.

Insufficient primary stability of acetabular hip cups is a complication resulting in early cup loosening. Available cup designs vary in terms of wall thickness, potentially affecting implant fixation. This study investigated the influence of different wall thicknesses on the implantation process and the resulting primary stability using excised human acetabula. Implantations were performed using a powered impaction device providing consistent energy with each stroke. Two different wall thicknesses were compared in terms of seating progress, polar gap remaining after implantation, bone‐to‐implant contact area, cup deflection, and lever out moment. Thin‐walled cups showed higher lever out resistance (p < 0.001) and smaller polar gaps (p < 0.001) with larger bone contact toward the dome of the cup (p < 0.001) compared to thick‐walled cups. Small seating steps at the end of the impaction process were observed if a high number of strokes were needed to seat the cup (p = 0.045). A high number of strokes led to a strain release of the cup during the final strokes (p = 0.003). This strain release is indicative for over‐impaction of the cup associated with bone damage and reduced primary stability. Adequate cup seating can be achieved with thin‐walled cups with lower energy input in comparison to thicker ones. Thin‐walled cups showed improved primary stability and enable implantation with lower energy input, reducing the risk of over‐impaction and bone damage. Additional strokes should be avoided as soon as no further seating progress has been observed.

We report on an infant, aged four months, suffering from a severe hemangioma of the left labium majus. We induced systemic treatment with propranolol in off-label-use over a period of 5 1/2 months. A few weeks after onset of the treatment, the size and color of hemangioma was obviously reduced; finally there was an almost complete regression. This result underlines the role of propranolol in treatment of problematic hemangioma.