SYNOPSISOn a cherchk ktendre l'utilisation de la chromatographie sur gel au domaine des molkules organiques de forte masse et des macromol&cules de faible masse. On a montrk que I'ktalonnage universe1 en volume hydrodynamique et l'ktalonnage en volume molaire peuvent &tre utilisCs dans le cas des petites mol6cules si la skparation sur le support chromatographique n'est pas perturb& par des phknomhes d'adsorption.
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