ImportanceSARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms or other health effects occurring after acute infection, termed postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. Characterizing PASC requires analysis of prospectively and uniformly collected data from diverse uninfected and infected individuals.ObjectiveTo develop a definition of PASC using self-reported symptoms and describe PASC frequencies across cohorts, vaccination status, and number of infections.Design, Setting, and ParticipantsProspective observational cohort study of adults with and without SARS-CoV-2 infection at 85 enrolling sites (hospitals, health centers, community organizations) located in 33 states plus Washington, DC, and Puerto Rico. Participants who were enrolled in the RECOVER adult cohort before April 10, 2023, completed a symptom survey 6 months or more after acute symptom onset or test date. Selection included population-based, volunteer, and convenience sampling.ExposureSARS-CoV-2 infection.Main Outcomes and MeasuresPASC and 44 participant-reported symptoms (with severity thresholds).ResultsA total of 9764 participants (89% SARS-CoV-2 infected; 71% female; 16% Hispanic/Latino; 15% non-Hispanic Black; median age, 47 years [IQR, 35-60]) met selection criteria. Adjusted odds ratios were 1.5 or greater (infected vs uninfected participants) for 37 symptoms. Symptoms contributing to PASC score included postexertional malaise, fatigue, brain fog, dizziness, gastrointestinal symptoms, palpitations, changes in sexual desire or capacity, loss of or change in smell or taste, thirst, chronic cough, chest pain, and abnormal movements. Among 2231 participants first infected on or after December 1, 2021, and enrolled within 30 days of infection, 224 (10% [95% CI, 8.8%-11%]) were PASC positive at 6 months.Conclusions and RelevanceA definition of PASC was developed based on symptoms in a prospective cohort study. As a first step to providing a framework for other investigations, iterative refinement that further incorporates other clinical features is needed to support actionable definitions of PASC.

Objectives To review the diagnostic accuracy of transvaginal ultrasound (TVS) in the preoperative detection of rectosigmoid endometriosis in patients with clinical suspicion of deep infiltrating endometriosis (DIE), comparing enhanced (E-TVS) and non-enhanced approaches. Methods 97% (95%CI,[95][96][97][98] 33.0 (95%CI,, respectively. Significant heterogeneity was found for sensitivity (I 2 , 90.8%; Cochran Q, 195.2; P < 0.001) and specificity (I 2 , 76.8%; Cochran Q, 77.7; P < 0.001). We did not find statistical differences between

Oral poster abstracts S-BOT (p = 0.05). M-BOT had echogenic fluid more than S-BOT, but this difference did not reach statistical significance. Only in 5/11 tumors (45%) a significant blood flow was documented. 11/23 (47%) tumors were correctly triaged for oncology-related surgery procedure based on clinical and sonographic evaluation. Conclusions: Echogenic fluid, multilocularity and a larger diameter is more typical to M-BOT. Papillary projections are more often associated with S-BOT. Correct triage for an oncology-related surgery, based on these factors, seem less successful than expected. Objective: The purpose of this study was to evaluate the intraobserver and interobserver agreement for identifying adnexal malignancy using color flow location in indeterminate masses after a gray-scale transvaginal sonography. Methods: Digitally stored color Doppler sonographic images, from a consecutive series of 130 women with an adnexal mass submitted to surgery after transvaginal sonography were evaluated by 6 different examiners with different degree of experience. Only consecutive cystic mass in which the gray-scale echo architecture was not suggestive of benign histology was included in the study. Solid excrescences or solid portions of the tumor were evaluated for vascular flow with color Doppler sonography. A mass was graded malignant if flow was shown within the excrescences or solid areas (central flow) and benign if there was no flow or only peripheral. Intraobserver and interobserver agreement according with the level of experience were assessed by calculating the kappa index. Results: Of the 130 consecutive cases with indeterminate findings at gray-scale evaluation, definitive histologic diagnoses were as follows: 80 (61.5%) benign and 50 (38.5%) malignant masses. Intraobserver agreement was good or very good for all examiners with different degree of experience (kappa ranging from 0.721 to 0.888). Interobserver agreement was good to moderate for all operators (kappa ranging from 0.478 to 0.714), irrespective of degree of experience. A correct classification was obtained by all assessors in 52% of malignant masses. Only ten masses (7.7%) were incorrectly classified by all the assessors. Conclusions: The use of color Doppler in the evaluation of flow location for the detection of adnexal malignancy seems to be reproducible method even in moderate experienced examiners. OP24.08 OP24.09Transrectal ultrasound in the evaluation of locally advanced cervical cancer after neoadjuvant chemotherapy Objective: We compared accuracy of transrectal ultrasound (TRUS) and magnetic resonance (MRI) in evaluation of locally advanced cervical cancer after neoadjuvant chemotherapy (NACT) in this study. Total 36 women with histologically verified cervical cancer stage IB2, incipient IIB and deep stromal invasion with response to NACT were included in this study. All patients were treated with ifosfamide/cisplatin chemotherapy followed by radical hysterectomy at our department in years [2004][2005][2006][2007][2008]. The histologica...

Objective To assess the feasibility of a specific training program for ultrasound diagnosis of adnexal masses. Methods

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