Sedation is used almost universally in the care of critically ill patients, especially in those who require mechanical ventilatory support or other life-saving invasive procedures. This review will focus on the sedation strategies for critically ill patients and the pharmacology of commonly used sedative agents. The role of neuromuscular blocking agents in the ICU will be examined and the pharmacology of commonly used agents is reviewed. Finally a strategy for rational use of these sedative and neuromuscular blocking agents in critically ill patients will be proposed.
In our practice we became interested in the use of Hyper saline after seeing some research on its use in calves and horses that was done at Ohio State University.
For years we had been using commercial fluid concentrates and diluting them for our fluid therapy. At best this procedure left much to be desired. Transporting large volumes of sterile water, calculating correct dilution, time required to administer fluids and cost to the client limited its use.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.