The abilities of fungi pathogenic and nonpathogenic to bean (Phaseolus vulgaris) to metabolize the phytoalexin phaseollin were compared when grown in shake cultures containing 12 to 15 [zg phaseollin/ ml. Under these conditions phaseollin was metabolized by five out of seven pathogens and by three out of five nonpathogens.Disappearance of phaseollin was accompanied by the appearance of metabolic products in cultures of Fusarium solani f. sp. phaseoli, Colletotrichurn lindemuthianum, Botrytis cinerea and Cladosporium herbarum. The nonpathogen C. herbarum detoxified phaseollin to la-hydroxyphaseollone as rapidly as the pathogen F. solani f.sp. phaseoB. Phaseollin was converted to 6a-hydroxyphaseollin by the pathogens B. einerea and C. lindemuthianum, and this product was further metabolized by the latter fungus. 6a-Hydroxyphaseollin was less fungitoxic to B. cinerea. C. lindemuthianum was equally sensitive to both compounds.Phaseollin was not metabolized by the pathogens Fusarium oxysporum f. sp. phaseoB and Thielaviopsis basicola.
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