This one-pot synthesis of sulfonimidamides provides a new structural modification approach for sulfonamides, and might benefit drug discovery and development in the future.

. Can. J. Chem. 53,3044 (1975).Reaction of alkyl(ary1)phosphines with xenon difluoride gives alkyl(aryl)hydridofluorophosphoranes which were characterized by proton and fluorine n.m.r. spectroscopy. With phenylchlorophosphines, substitution of chlorine by fluorine accompanied oxidative-fluorination to give phenylfluorophosphoranes, (C6H5).PF5-.. With tert-butylchlorophosphines, chlorination of the tert-butyl group accompanied oxidative-fluorination, and a mixture of products was obtained. Reaction of xenon difluoride with methyl iodide gives methyliodine(II1) difluoride, characterized by proton and fluorine n.m.r. spectroscopy.Silicon-sulfur and silicon-nitrogen bonds are cleaved by xenon difluoride and an intermedi-' ate containing a xenon-nitrogen bond is postulated.Reaction of xenon difluoride with hexafluoroacetone, perfluoropinacol, or disodium perfluoropinacolate failed to give stable xenon esters.

The cyclic amido-structure of 2-pyridone, 6-methyl-Z-pyridone, 2-quinoloce, and 4-methyl-2-quinolone in the solid state and in solution has been confirmed by infrared measurements. The spectra of sodium 2-pyridyl oxide and potassium 2-quinolyl oxide have also been examined and a chelated structure for potassium 2-quinolyl oxide is suggested to explain its inertness in the Kolbe-Schmitt reaction.IT is well known that the pyridones and analogous compounds are tautomeric with respect to the keto and the enol forms. For 2-pyridone these are represented by (I) and (11) respectively, probably being stabilised by resonance with the dipolar forms (111) and (IV). ) showed by a study of the ultraviolet absorption spectra that in methanolic solution 2-ar,d 4-pyridone exist substantially in the amido-form. Addition of alkali led to marked spectral changes which were ascribed to a change towards the enol form. The spectrum of 3-hydroxypyridine, however, was not greatly affected by either alkali or acid. Leis and Curran ( J . Amer. Chem. SOC., 1945, 67, 79), on the basis of the dipole moment for a dioxan solution, concluded that in this solvent 4pyridone

The influence of steric factors in substitution reactions of 2 : 7 dihydroxyand 2 : 7-diamino-naphthalenes is discussed, and additional evidence obtained that one of the bromine atoms in dibromo-2 : 7-dihydroxynaphthalene is in position 6. * Fieser's very general statement * beginning " Fieser and Lothrop investigated various 1 : 8-dialkyl derivatives of 2 : 7-dihydroxynaphthaleneI" although probably correct, cannot be supported from the literature. Indeed, simple 1 : 8-dialkyl-2 : 7-dihydroxynaphthalenes have only recently been described .sThe literature relevant to this topic is slight.

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The reaction of xenon difluoride in acetonitrile solution with some organosilicon compounds is reported.

Abstract The adduct of 2,2,2-trifluoro-4,4,5,5-tetrakis(trifluoromethyl)-1,3,2 A 5 -dioxaphospholane with trimethylphosphine crystallises in the orthorhombic space group Pbcm, Z = 4, with a - 11.018(2), b - 12.978(4), c= 11.607(2) Å at -120 °C. The perfluoropinacolyl ring system lies in a crystallographic plane of symmetry. This ring conformation and the very long endocyclic C-C bond and average C-CF3 distances of respectively 1.59(1) and 1.59(1) A are presumably a consequence of very short F···F steric contacts. The P→P bond distance of 2.234(5) is very short for a coordinate bond being only 0.01-0.03 A longer than that typically observed for a a-bond. The tr-bond lengths to the hexacoordinate phosphorus are influenced by the nature of the Zrans-bond in the octahedron.

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