The study explored the influence of supply chain management practises on operational performance in the manufacturing firms in Nigeria. Conversely, the study adopted the cross-sectional survey research design. Data were primarily sourced through administered questionnaires. A collection of four thousand, nine hundred and eighty-four (4,984) employees of all manufacturing firms listed on the Nigerian Stock Exchange (NSE) and operating in Nigeria's Edo and Delta States make up the study's population. A sample size of 370 was computed using the Yamane’s formula and same number of questionnaires was administered but 318 were found fit in testing the formulated hypotheses. Research data were analyzed, using descriptive and inferential statistical instruments. Based on the ordinary least squares regression, the study revealed that procurement outsourcing (?= 0.082974, t-Statistic= 3.049313 and p<0.05) and order process management (?= 0.349839, t-Statistic= 7.972484 and p<0.05) have positive and statistically significant relationship with operational performance of quoted manufacturing firms in Nigeria. Based on these conclusions, the study suggested that management of manufacturing firms conduct a benchmarking exercise for best players in the industry as a way to improve their procurement outsourcing practices, and that the facility and competence of order processing system should be routinely evaluated using indicators that tracked the flexibility and dependability of order handling. This would allow them to attain and keep up supply chain performance that is unmatched.
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