Healthcare information, technology, product of technology, and information technology that supports the development of healthcare can be resulted from research and development of science and technology. The presidential regulation stated that the components of the healthcare management were grouped into sub-systems that handle the management, information, and regulation regarding the healthcare itself. Therefore, this work was aimed to provide a design of the integrated e-health system in Bangli District, Bali. Enterprise Application Integration (EAI) approach was used in this health information system integration strategic planning. The results provided the identification of the business process and its challenges of the current system. Method of network infrastructure connection was also provided. The design was also covered the future planning of development which based on their priority for the next five years, including the challenges for bigger integration to the systems that were built by departments from other related fields. Keywords-Bangli; e-health; enterprise application integration health information system; system integration.