Dois novos alcalóides indólicos com esqueleto plumerano, spruceanuminas A (1) e B (2), e oito alcalóides indólicos conhecidos, aspidospermidina (3), desmetoxipalosina (4), aspidocarpina (5), aspidolimina (6), fendlerina (7), aspidolimidina (8), obscurinervidina (9) e obscurinervina (10), foram isolados do extrato metanólico das cascas do caule e sementes de Aspidosperma spruceanum. As estruturas dos compostos foram elucidadas com base na análise de dados espectroscópicos, principalmente os obtidos por espectros de RMN 1 H e 13 C (1D e 2D) e por espectrometria de massas. Two novel indole alkaloids with plumeran skeleton, spruceanumines A (1) and B (2), and eight known indole alkaloids, aspidospermidine (3), demethoxypalosine (4), aspidocarpine (5), aspidolimine (6), fendlerine (7), aspidolimidine (8), obscurinervidine (9) and obscurinervine (10) were isolated from stem bark and seeds methanolic extracts of Aspidosperma spruceanum. Compounds structures were elucidated on the basis of spectroscopic data, mainly those obtained by 1 H and 13 C NMR (1D and 2D) and mass spectrometry.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.