In present day societies, cancer is a widely spread disease that affects a large proportion of the human population, many research teams are developing algorithms to help medics to understand this disease. In particular, tumor growth has been studied from different viewpoints and different mathematical models have been proposed. Our aim is to make predictions about shape growth, where shapes are given as domains bounded by a closed curve in R 2 .These predictions are based on geometric properties of plane curves and vectors. We propose two methods of prediction and a comparison between them is shared. Both methods can be used to study the evolution in time of any 2D and 3D geometrical forms such as cancer skin and other types of cancer boundary. The first method is based on observations in the normal direction to the plane curve (boundary) at each point (normal method). The second method is based on observations at the growing boundaries in radial directions from the "center" of the shape (radius method). The real data consist of at least two input curves that bind a plane domain.
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