ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pulmonary hypertension in children is commonly caused by underlying cardiac and pulmonary disease. Within the past 10 years, scurvy has been identified as a cause for pulmonary hypertension. We describe the case of a 3-year-old autistic boy with undiagnosed scurvy who was scheduled for cardiac catheterization. Immediately after induction, the patient became hemodynamically unstable, which worsened with administration of nitrous oxide. Cardiac catheterization revealed pulmonary hypertension, which dramatically improved with administration of vitamin C. Anesthesiologists should be aware that scurvy is more common than previously thought, even in developed countries and can cause unexpected circulatory collapse from pulmonary hypertensive crisis.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Formation of Indoles and 3,1-Benzoxazines from o-Alkenylanilides andDimethyl(methylthio)sulfonium Trifluoromethanesulfonate. -Substrates bearing an N-sulfonyl group yield indole derivatives without any detection of thio derivatives. N-Benzoyl-or acetyl substrates lead to formation of 4-methylthiomethyl-3,1-benzoxazines (VII). Substrate (VIII) bearing an unsubstituted alkene moiety affords 3-methylthio-N-tosylindoline (IX). Finally, benzofuran (XI) is formed from the allylsubstituted phenol (X). -(OKUMA*, K.; YASUDA, T.; TAKESHITA, I.; SHIOJI, K.; YOKOMORI, Y.; Tetrahedron 63 (2007) 34, [8250][8251][8252][8253][8254] Dep. Chem., Fac. Sci.,
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