Background: Some studies have addressed the prevalence of human papillomavirus (HPV) in head and neck cancer in South America; however, no studies have systematically gathered prevalence and conducted a meta-analysis. Aim: This study aims to estimate the prevalence of HPV in oral and oropharyngeal squamous cell carcinomas in South America. Methods: We performed a systematic review and meta-analysis using the following databases: PubMed, Embase, Lilacs, Medline, Scopus, and Web of Science. Data were extracted and analyzed using random-effects models to estimate the pooled prevalence of HPV. Results: We identified 209 nonduplicated studies, of which 38 were selected. The overall prevalence of HPV was 24.31% (95% CI 16.87–32.64; I2 = 96%, pheterogeneity <0.001). HPV prevalence in oropharyngeal cancer was 17.9% (95% CI 7.6–31.4; I2 = 96%, pheterogeneity <0.001) and that in oral cavity cancer was 23.19% (95% CI 14.94–32.63; I2 = 94%, pheterogeneity <0.001). Conclusions: We found an overall prevalence of HPV in 24.31% of oral and oropharyngeal squamous cell carcinomas in South American patients. The prevalence of HPV was 17.9% for oropharyngeal cancer and 23.19% for oral cavity cancer.
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Aims: To investigate the prevalence of common mental disorders among medical students at the Federal University of Rondônia Foundation. Study design: Cross-sectional study. Place and Duration of Study: Department of Medicine, Federal University of Rondônia Foundation (UNIR), in October 2019. Methodology: Cross-sectional study was conducted in October 2019, using a questionnaire adapted with the Self-Report Questionnaire 20 (SRQ-20). Sample: 116 students, 56 females and 60 males, from different periods completed the questionnaire. The prevalence of positive results in the SRQ-20 and the variance of positive responses were verified. Results: The prevalence of positive results for the SRQ-20 was estimated at 69.8% (95% CI 61.0-78.6; 81 cases). No difference was found in the proportions of positive results for the variables analyzed (p >.05). There was no significant association between the calculated prevalence ratios and the factors analyzed (p >.05). The symptoms related to the reduction in vital energy showed the highest average amount of positive responses (76 [± 10.4]; p <.01). Conclusion: The prevalence of positive results for the SRQ-20 observed in our study was much higher than the average reported for Brazilian medical students. The number of students who said they thought about suicide was also high. We understand that these findings reinforce the need for the development and implementation of medical students' mental health care programs to identify, monitor, and, if possible, adequately treat these cases.
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