Klebsiella pneumoniae is an opportunistic pathogen with various virulence factors that give it the capability to invade a host. Nevertheless, the treatment of bacterial infection is gradually complicated as the bacteria can develop resistance to antimicrobial agents. As nanotechnology is a prosperous field for researchers, we employed zinc oxide (ZnO) nanoparticles (NPs) on isolates of Klebsiella pneumoniae. Here, we studied the effect of three NP concentrations—0.25, 0.50, and 0.75 mM—on the gene expression of Klebsiella pneumoniae capsules in isolates collected from different samples. After conducting an anti-bacterial test, the highest nine types of bacteria that resisted the antibacterial agent were chosen for further examination. The gene expression of four genes responsible for capsule manufacturing, namely magA, k2A, rmpA, and kfu, were investigated. When the NP concentration was 0.25 mM, the lowest efficiency was obtained. However, when the concentration increased to 0.50 mM, a noticeable effect on gene expression was detected; consequently, at a concentration of 0.75 Mm, the highest impact was achieved and the gene expression was stopped.
This review focuses on organotin toxicity and its effect on human health. Organotins are utilized widely as anti-tumor, anti-inflammatory, anti-fungal, or antimicrobial agents in both agricultural and industrial applications. These materials are more toxic than inorganic cans which are poorly absorbed and are excreted on the surface of the can, which consequently results in increasing the level of toxicity to a variety of organisms and damaging the environment. An investigation of chemical compounds in organotin led to different methods for quantifying and qualifying individual molecules. Tributyltins, a highly toxic component of organotin, have recently been given great attention.
Background: COVID-19 is an ongoing disease that caused, and still causes, many challenges for humanity. In fact, COVID-19 death cases reached more than 4.5 million by the end of August 2021, although an improvement in the medical treatments and pharmaceutical protocols was obtained, and many vaccines were released. Objective: To, statistically, analyze the data of COVID-19 patients at Alshifaa Healthcare Center (Baghdad, Iraq). Methods: In this work, a statistical analysis was conducted on data included the total number, positive cases, and negative cases of people tested for COVID-19 at the Alshifaa Healthcare Center/Baghdad for the period 1 September – 31 December 2020. The number of people who got the test was 1080, where 424 were infected and the rest of them were not. Results: The study showed that males’ infection and death cases were higher than females by more than double, despite the population ratios of the two genders being almost equal. Furthermore, as the age of patients is older, the chance of death is higher. Death cases were lower in December than the previous three months, which could be attributed to lower infection cases compared with the previous months. Conclusions: We can conclude that the peak of infected ages was the same as the other countries. Hence, the number of checked children was low, while we have the peak around the 40s and 50s. Females’ death cases were much less than males, which could be attributed to the genetic influence and the higher responsibility that females showed than males to prevent the disease’s spreading.
Organotin(IV) compounds have seen a marked increase in industry utilization over the years and exhibited enormous economic benefits as well as environmental costs due to their numerous industrial, medical, and agricultural uses and other applications. The present review is a continuation of aseries of reviews on the use of organotin(IV), chemicals, synthesis, characteristics and geometry as well as the industrial and biological applications.
SARS-CoV-2 virus(COVID-19), the cause of coronavirus disease, has several variations.Some are thought to be particularly important or have been said to be so, because of their potential for greater transmissibility, Virus pathogenicity has grown, or vaccinations against them have become less effective. These mutations have a role in the COVID-19 pandemic's persistence. The B.1.1.529-Omicron variant, found in many coronavirus cases reported in South Africa discovered late 2021, having a surprisingly great number of mutations which raise a concern toward the spreadablity of this variant and severity of illness in comparison to other corona virus variants as well as the effectivity of the available vaccinations. This review summarizes of the most recent information and the answers to most of the world's questions about Omicron.
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