Aim of the work: diagnosis of liver metastases is of essential importance in the staging of patients with a known primary tumor. So, the present study aimed to evaluate role of DWI in diagnosis of liver metastasis. Patients and methods: twenty patients were included in this study. The cases were evaluated over 6 months at Ain Shams University Hospital with a 1.5 Tesla Phillips (MR System Achieva) whole body imager. Results: in the sample of the study which was composed of 20 patients, there were two patients who presented with negative lesion in DW MRI with sensitivity 100%, specificity 90% and accuracy 95%. Conclusion: DWI alone performed equally well as Gd-MRI in the diagnosis of liver metastases. In cases where gadolinium injection was not allowed, dynamic contrast-enhanced imaging can be replaced by a protocol based on unenhanced T1-and T2-weighted imaging combined with DWI. Recommendations: further studies on larger scale of patients are needed to confirm the results of the study.
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