The present study suggests that a combined course of Er:YAG and Nd:YAG laser therapy may be beneficial particularly in inaccessible areas such as deep pockets on a short-term basis. Further, well-designed studies are required to assess the effectiveness of the combination of these lasers.
Objective
The aim of the study is to evaluate saliva and gingival crevicular fluid (GCF) levels of suPAR and galectin‐1 in different periodontal health status and relationship between these molecules and TNF‐α to understand the roles of these molecules in periodontal inflammation process.
Background
Soluble urokinase plasminogen activator receptor (suPAR) has been described as a biological marker of inflammation and immunological activation. Galectin‐1, a member of the galectin family, is an anti‐inflammatory cytokine. However, to date, levels of these two molecules in periodontal health and disease have not been well documented.
Methods
A total of 60 individuals, 20 with chronic periodontitis (group P), 20 with gingivitis (group G), and 20 with healthy periodontium (group H) were recruited for this study. Full‐mouth clinical periodontal measurements were recorded in periodontal charts. GCF and whole saliva samples were collected to determine the levels of suPAR, galectin‐1, and TNF‐α in study groups using enzymelinked immunosorbent assay (ELISA) method.
Results
The GCF total amount of suPAR, galectin‐1, and TNF‐α in GCF was similar in group P and G (P > .05). The GCF total amounts of these molecules in GCF were higher in the group G and P compared to the group H (P < .05), whereas the GCF concentrations of suPAR and galectin‐1 were lower in the group G and P compared to the group H (P < .05).The saliva concentration of suPAR was significantly higher in group P compared to the group G and H (P < .05). It was also higher in the group G compared to the group H but there is no significant difference between the groups (P > .05). Salivary galectin‐1 levels were similar in the study groups (P > .05).
Conclusion
Increased levels of GCF suPAR, galectin‐1, and saliva suPAR in periodontal disease suggest that these molecules may play a role in the periodontal inflammation. suPAR and galectin‐1 may be considered as potential biomarkers in periodontal disease.
This in vivo study aimed to do a biomechanical analysis of the early period bone-implant connection of titanium implants simultaneously inserted with xsenogenic and allogenic bone ring. In this study, 28 Sprague Dawley female rats were used. Four rats were killed to obtain an allogenic bone ring, and after this, the remaining rats were divided into control (n = 8), xsenogenic (n = 8), and allogenic (n = 8) bone ring groups. Titanium-machined surfaced implants were integrated right tibias of the rats. In controls, only implants were integrated into right tibias. In the greft groups, the implants were integrated simultaneously with bone rings. After 2 weeks of the experimental period, the rats were killed ,and titanium implants and surrounding bone tissues were removed for biomechanic analysis. After biomechanical reverse torque analysis bone-implant connection was determined as Newton/cm 2 ; in controls 3.26 (1.2 to 4.5), in allogenic ring group 3.37 (2 to 4.4), in xsenogenic ring group 5.93 (2.8 to 10). Statistically significant differences were not detected between the groups (P > 0.05). Within the limitation of this study, both allogenic and xsenogenic bone grafts could be successfully used in bone augmentation in implant surgery.
In this study, the authors aim to investigate the effect of dual antiplatelet agents on peri-implant-guided bone regeneraation by studying a sample of rats with titanium implants in their tibias. The rats were randomly divided into 5 groups: acetylsalicylic acid (ASA) (n = 10), treated with 20 mg/kg of ASA; ASA+CLPD (Clopidogrel): (n = 10), treated with 20 mg/ kg of ASA and 30 mg/kg of clopidogrel; ASA+PRSG (Prasugrel): (n = 10), treated with 20 mg/kg of ASA and 15 mg/kg of prasugrel; ASA+TCGR (Ticagrelor): (n = 10), treated with 20 mg/kg of ASA and 300 mg/kg of ticagrelor; and a control group (n = 10) received no further treatment after implant surgery. Bone defects created half of the implant length circumferencial after implant insertion and defects filled with bone grafts. After 8 weeks experimental period, the rats sacrified and implants with surrounding bone tissues were collected to histologic analysis; bone filling ratios of defects (%) and blood samples collected to biochemical analysis (urea, creatinine, aspartate aminotransferase, alanine aminotransferase, phosphorus, magnesium, alkaline phosphatase, calcium, and parathormone). A statistically significant difference was not detected between the groups for all parameters (P > 0.05). When the percentage of new bone formation was examined, it was found that there was no statistically significant difference between the groups (P > 0.05). Antiplatelet therapy may not adversely affect guided bone regeneration in peri-implant bone defects.
Background:
The aim of this study was to evaluate the prevalence of lingual cortical bone perforation caused by virtually placed implants on cone-beam computed tomography images in the edentulous mandibular canine region and determine the relationship between the morphological structure of the crest and the risk of perforation.
Methods:
Eight hundred dental implants were virtually inserted on 100 qualified cone-beam computed tomography scans. Crests were divided into 4 groups according to the crest morphology as Type U, Type L, Type P, and Type C. The distance between the implant tip and lingual plate was measured using a digital caliper. Incidence of lingual plate perforation and proximity of the implant tip to the lingual plate were measured for 4 types of the alveolar crest.
Results:
A total of 800 virtual implant applications were performed in 100 patients who met the inclusion criteria. The incidence of lingual plate perforation was found to be significantly higher in Type U crests than in the other types. It was also found to be statistically significantly higher in Type L crests than in Type P and Type C crests. When the relationship between implant length and perforation was evaluated, perforation in 14 mm implants was significantly higher than 8, 10, and 12 mm implants.
Conclusions:
According to the results of this study, it was determined that high rates of perforation occurred in the U and L type crests and 14 mm implants during implant surgery in the mandibular anterior edentulous region.
İnternet Ortamındaki Dişeti Hastalığı ile İlgili Bilgilerin Okunabilirlik Analizi
Amaç: Bu çalışma, internet ortamında bulunan dişeti hastalığı ile ilgili Türkçe metinleri okunabilirlik açısından değerlendirmeyi amaçlamıştır.
Gereç ve Yöntemler: “Dişeti hastalığı” anahtar kelimeleri kullanılarak Google arama motorundan arama yapıldı. Arama sonucunda hasta bilgilendirmesi ile ilgili Türkçe metin içeren ilk 50 sayfa çalışmaya dahil edildi. Metin kaynakları üniversite hastanesi, özel sağlık kuruluşu, periodontoloji uzmanı, diş hekimi, ağız diş sağlığı merkezi ve meslek örgütü olacak şekilde kaydedildi. Elde edilen hasta bilgi metinleri Ateşman Okunabilirlik İndeksi'ne göre değerlendirildi.
Bulgular: Arama sonucu çıkan ilk 50 sitenin 48 tanesi dahil edilme kriterlerini karşılıyordu. Metinler kaynaklarına göre katagorize edildiğinde; özel sağlık kuruluşları (%79.17) , üniversite hastaneleri (8.33), periodontoloji uzmanı (4.17), diş hekimi (4.17), ağız diş sağlığı merkezi (2.08) ve meslek örgütü (2.08) tarafından oluşmaktaydı. Değerlendirilen metinlerin %83.34’ü orta düzeyde okuma zorluğundaydı.
Sonuç: Bu çalışmanın sonuçlarına göre, Türkçe web sitelerinde “Dişeti hastalığı” ile ilgili bulunan hasta bilgilendirme metinlerinin orta düzeyde okuma güçlüğüne sahip olduğu tespit edilmiştir. İnternet sitelerinde bulunan bu metinler içerik açısından yeterli olsalar da hastalar tarafından anlaşılmadıkları takdirde okuyucular üzerinde amaçlanan etkileri görülmeyecektir. Bu nedenle hasta eğitim ve bilgilendirme metinlerinin yayınlanmadan önce daha kolay okunabilmesi için okunabilirlik araçları tarafından değerlendirilmesi faydalı olacaktır.
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