The emerging evidence on oral manifestations of the coronavirus disease (COVID-19) has provoked large debates about their etiology, prognosis, and significance; however, these symptoms may have been underreported and discovered by accidental diagnosis due to the inability of the COVID-19 patients to seek oral health care and the low fatality of the oral mucocutaneous lesions. Larger case series following rigorous reporting guidelines are highly required to enhance evidence robustness; therefore, we aim to demonstrate the characteristics of 26 laboratory-confirmed COVID-19 patients with tongue ulcers according to the CARE guidelines (Gagnier et al., 2013;Riad, Klugar, & Krsek, 2020).The demographic, clinical, and laboratory characteristics of the patients who visited our department with tongue ulcers in April -June 2020 were retrospectively extracted from the hospital records.
We have read with great interest the review of Iranmanesh et al.(2020) on oral manifestations of coronavirus diseases which demonstrated the emergence of aphthous-like lesions in 16 cases thus suggesting that neutrophil chemotaxis, stress, and
To conclude, AC of COVID-19 patients can be attributed to numerous local irritants, including hypersalivation. Further epidemiologic studies are warranted to investigate the potential predisposing factors for AC emergence in COVID-19 patients.
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