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Background: Red blood cell distribution width (RDW) is a quantitative marker of heterogeneity of circulating erythrocytes size and a marker of malnutrition, inflammation and mortality. Erythropoietin resistance index (ERI) is considered as an effective way to check erythropoietin resistance. ERI is related to all-causes of morbidity & mortality in hemodialysis patients. Association with aging and gender have also confirmed progressive increase in RDW with aging and in female gender.Objective: this study aimed to check the relation between RDW & ERI in iron replete hemodialysis patients. Patients and methods: 89 patients matched inclusion criteria followed up for 12 months and data analyzed including age, gender, diabetic status, serum iron, serum ferritin, red blood cell width, Erythropoietin dose per week per kg body weight. Results: Patients included were 36 (40.5%) females and 53(59.5%) males with mean age of 42.7 ± 15.2 years old. Diabetic patients were 51 (57.3%) and non-diabetic were 38 (42.7%). All patients were iron replete as per inclusion criteria with serum ferritin 200-800 ug/dl and transferrin saturation 20-40%. Hemoglobin, RDW & ERI were repeated at 4 checkpoints during the 12-months follow-up period. The average of all (4) readings then processed for Pearson correlation logistic regression to identify the relation between RDW and ERI and we found linear correlation between RDW and ERI. R-square 0.158, P-value < 0.001, this relation was independent of age, gender, hemoglobin level, erythropoietin dose and diabetic status. Conclusion: Our results confirmed the independent relation between RDW and resistance to erythropoietin in iron replete hemodialysis patients.

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Accurate staging of gastric cancer is clinically important because the prognosis and choice of an optimal therapeutic approach are directly related to the stage of a neoplasm at time of presentation. The tumor-node metastasis (TNM) staging system is one of the most commonly used staging systems. Multi-detector CT (MDCT) is a powerful test for non-invasive evaluation of gastric cancer. MDCT not only detect primary tumors but also provide comprehensive staging, with accurate assessment of the neoplastic mass, regional and distant lymphadenopathy, and distant metastasis. to evaluate & comparison the role of multidetector CT with MPR images & upper endoscopy in the staging of gastric carcinoma. Inclusion criteria were patients who had histologically proven adenocarcinoma of the stomach based upon an upper gastrointestinal endoscopic biopsy. Water might have been utilized to gastric extension for 18 patients (10 men Also 8 women). On 2 patients, gas might have been utilized for gastric extension (1 mamoncillo Also 1 woman). MDCT for MPR might have been exceptionally of service in figuring out those profundity from claiming Attack of gastric tumor for generally correctness about 90. 9% to assessing serosal inclusion with/ without contiguous organ Attack. MDCT will be a handy device for TNM organizing for gastric carcinoma. S were as from claiming MPR pictures need enhanced those symptomatic precision about MDCT. Arranging about gastric malignancy empowers the Choice of the more effective What's more safer medication methodologies. Though whatever imaging technobabble may be recognized in the preoperative work-up, ct examine ought further bolstering be viewed Similarly as those modality from claiming decision.