Restoring noncarious cervical lesions are challenging to clinical practice. This study aimed to compare the clinical performance/longevity of glass ionomer cements (GIC) and composite resins (CR) used for noncarious cervical lesions (NCCL) through a systematic review and meta-analysis (MA). Data: Randomized and controlled clinical trials and nonrandomized clinical trials, which compared the clinical performance/longevity of CR and GIC (conventional and/or resin-modified) in the treatment of NCCL, were included. Source: The methodological quality and risk of bias were evaluated using the Cochrane Collaboration tool. Seven MAs were performed considering (1) the clinical performance of the parameters in common: retention, marginal discoloration, marginal adaptation, secondary caries, color, anatomic form, surface texture and (2) a follow-up time of 12, 24 and 36 months. The prevalence of successful restorations and the total number of restorations per clinical parameter/follow-up time were used to calculate the relative risk (95% CI). Study selection: After screening of the studies, 13 studies were used for quantitative synthesis. The risk difference (CI 95%, α, I 2 ) between GIC and CR for anatomic form was 0.00 (-0.02, 0.02; p ¼ 0.83; 0%); for color was -0.02

Relevant public policies in oral health have been implemented in Brazil since 2004. Changes in the epidemiological status of dental caries are expected, mainly in the child population. This study aimed to assess the dental caries experience and associated factors among 12-year-old children in the state of São Paulo, Brazil. A cross-sectional population-based study was conducted with data obtained from 415 cities, including a total of 26,325 schoolchildren who were included by the double-stage cluster technique, by lot and by systematic sampling. The statistical model included data from the São Paulo Oral Health Survey (SBSP 2015), the Human Development Index (HDI) and the Social Vulnerability Index (SVI). A theoretical-conceptual model categorized the variables into three blocks, namely, contextual (HDI, SVI, region of residence and fluoridation of water), individual (sex and ethnicity) and periodontal conditions (gingival bleeding, dental calculus and the presence of periodontal pockets), for association with the experience of caries (DMFT). Statistically significant associations were verified by hierarchical multivariate logistic (L) and Poisson (P) regression analyses (p < 0.05). The results showed that 57.7% of 12-year-old children had caries experience. Factors that determined a greater prevalence of dental caries in both models were nonwhite ethnicity (OR L = 1.113, OR P = 1.154) and the presence of gingival bleeding (OR L = 1.204, OR P = 1.255). Male children (OR L = 0.920 OR P = 0.859) and higher HDI (OR L = 0.022), OR P = 0.040) were associated with a lower prevalence of dental caries experience. Water fluoridation was associated with a lower DMFT index (OR P = 0.766). Dental caries experience is still associated with social inequalities at different levels. Policymakers should direct interventions towards reducing inequalities and the prevalence of dental caries among 12-year-old children.

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Objetivo: Avaliar in vitro atividade antimicrobiana do a-terpineol, cinamaldeído, hipoclorito de sódio 1%, clorexidina 0,12%, e corega® em biofilme de Candida albicans (ATCC 90028) desenvolvidos sobre superfícies de reembasador protético macio. Metodologia: Espécimes do reembasador Bosworth Trusoft (Bosworth Company- USA) foram confeccionados de acordo com instruções do fabricante e foi induzida a formação da película salivar artificial por 60 minutos, a 37°C. O biofilme foi semeado (1x106 UFC/mL), sendo, após adesão inicial (24h, 37°C) expostos ao a-terpineol (10 mg/mL), cinamaldeído (10 mg/mL), hipoclorito de sódio 1%, clorexidina 0,12%, corega e solução salina (controle crescimento). Os espécimes permaneceram por 1 ou 10 minutos, em cada solução, sendo as exposições realizadas 24h, 48h e 72 h após a semeadura do biofilme. Avaliou-se a atividade metabólica, pelo teste de MTT e dureza Shore A, utilizando-se microdurômetro. A análise estatística foi realizada pelos testes  de Kruskal-Wallis/ Mann Whitney e teste t  (α=5%). Resultados: Observou-se que para a exposição por 1 min o cinamaldeído, clorexidina e hipoclorito foram eficientes (p>0,05). Aos 10 minutos, o a-terpineol apresentou atividade similar ao controle de crescimento (p>0,05) diferindo das demais substâncias.  Em relação à dureza, não houve diferença entre os grupos, apenas para o hipoclorito de sódio e corega. Conclusão: O cinamaldeído, clorexidina e hipoclorito demonstraram atividade antifúngica sobre biofilme de Candida albicans sobre superfície de reembasador protético.

Aim Evidence of glucose supplementation effect on Candida biofilm metabolism has not been demonstrated. Therefore, the aim of the present study was to evaluate the effect of glucose concentration on Candida biofilms. Methods Single‐ and dual‐species biofilms of Candida were grown on saliva‐coated poly(methyl‐methacrylate) disks for 72 hours. Biofilms (N = 8/group) were exposed to the following concentrations of glucose: 100 mmol/L (G100), 300 mmol/L (G300), and no glucose (G0: control). Biofilms were collected to determine the acidogenicity, viability, amount of soluble and insoluble extracellular polysaccharides (IEPS), and surface roughness. Data were analyzed using analysis of variance and Tukey's tests (α < 0.05). Results Single‐ and dual‐species biofilms from G300 were more acidogenic at 48 and 72 hours compared to G100 and G0 (P < 0.05). The viability of the G100 and G300 groups did not differ (P > 0.05), but differed statistically from G0. The amount of IEPS in the G300 group was statistically higher than the G0 and G100 groups (P < 0.05). The G300 group also presented a higher IEPS proportion per number of viable cells compared to others. G300 presented greater surface roughness for both single‐ (mean roughness = 1460 μm) and dual‐species (mean roughness = 1990 μm) biofilms. Conclusions Higher glucose concentration (300 mmol/L) during biofilm development favors the growth of single‐ and dual‐species biofilms of Candida.

Resumo Introdução As resinas compostas são alternativas restauradoras, porém sua superfície pode favorecer o acúmulo de biofilme. Objetivo Analisar in vitro a adesão de biofilmes de Streptococcus mutans (UA159) e Candida albicans (ATCC 90028) em superfícies de resinas compostas convencionais e bulk fill. Material e método Foram utilizadas quatro marcas de resinas compostas e bulk fill: Aura Bulk Fill - SDI®; Premisa - Kerr®; Opallis- FGM®, e Filtek bulk fill flow - 3M®. Utilizou-se saliva artificial para formação da película salivar, por 60 min a 37 °C. O inóculo foi padronizado em 1×108 UFC/mL para S. mutans e 1×106 UFC/mL para C. albicans. Os espécimes (n=8/grupo) foram acondicionados em placas de 24 poços, com BHI suplementado com sacarose para as bactérias, e RPMI 1640, para os fungos. A formação do biofilme foi avaliada considerando as unidades formadoras de colônia (UFC/mL).Os dados foram analisados por ANOVA e Tukey (p<0,05). Resultado Para os biofilmes de S. mutans, não houve diferença significativa na contagem de UFC/mL entre os diferentes tipos de resina (p=0,119). Na contagem de UFC/mL para biofilme de Candida, as médias variaram entre 7,78 e 8,34. Houve diferença significativa entre as marcas, especialmente entre as resinas convencionais e bulk fill. Conclusão O presente estudo demonstra que não há diferença na adesão para biofilmes de S. mutans. Porém, há diferença na adesão da C. albicans na superfície de diferentes resinas compostas.