1,2,4,5‐Tetrahydro‐3,2‐benzothiazepine 3,3‐dioxides 2, with a variety of substituents on the nitrogen atom, can be easily obtained by the title reaction. The isomeric compounds 4–6 are also formed from sulphonamides bearing an N‐aralkyl group with a chain of two or more carbon atoms. Activation of the ring closure‐position or deactivation of the aromatic ring in the substituent can direct the reaction to give compounds 2. Cyclization results are influenced by the size of the new heterocycle ring and by the predominant formation of derivatives with the SO2 group outside the ring.
Short Communicationssaid that no attempt was made to correct the Ivalues in this particular stationary phase for interfacial adsorption; in that case an entirely different picture might be observed.The Ivalues obtained at 12OOC on the more nonpolar stationary phases used (squalane, Apiezon L, and methylvinylsilicone) decreases while the 0-0 bond stretching vibrational (Raman) frequencies (VO-0) of the diperoxide molecules [7] increases ( Figure 4). This latter parameter corresponds to the peroxidic bond force constant and the geometry of the molecules of the solutes considered. As a matter of fact, significant differences in the activation parameters for the unimolecular homolyses of the above kind of diperoxides had been observed [8], behavior which can be related with the VO-0 Raman frequencies of those molecules. On the more polar stationary phases used (Ucon Oil LB 550X and Carbowax 20M) the linear correlationis no longer maintained, probably due to specific interactions between the diperoxide molecules and the characteristics of the stationary phases.
References[l] M. V.
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